DNA Binding and Cleavage Activities of Na[B(Glu)(OH)2]•2H2O, Na[B(Cit)(OH)2]•2H2O, Li[B(Sal)(OH)2], and Mg[B(Sal)(OH)2]•2H2O Complexes
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Hindawi Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The interaction of some previously reported complexes Na[B(Glu)(OH)(2)]center dot 2H(2)O, Na[B(Cit)(OH)(2)]center dot H2O, Li[B(Sal)(OH)(2)], and Mg[B(Sal)(OH)(2)]center dot 2H(2)O with cattle genomic DNA (CG-DNA) was investigated using UV absorption, viscosity measurements, and fluorescence studies. These complexes interact with DNA through the intercalative mode of binding. In addition, the DNA cleavage activity of the complexes in presence of H2O2 was determined using agarose gel electrophoresis. All complexes exhibit moderate ability of cleavage to the DNA.
Açıklama
Anahtar Kelimeler
Crystal-Structure, Aqueous-Solution, Metal-Complexes, Lithium-Salts, Boric-Acid, Borate, Bis(Salicylato)Borate, Fluorescence, Copper(Ii), Cobalt(Ii)
Kaynak
Journal of Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
2013
