Evaluation of hepatitis b virus and hepatitis c virus frequency in hemodialysis patients
Küçük Resim Yok
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: This study aimed to investigate the prevalence of the hepatitis B virus and hepatitis C virus in patients undergoing hemodialysisin Karabuk city.Material and Methods: For patients presented to the Karabuk University Training and Research Hospital for hemodialysis betweenJanuary 2016 and December 2018, HBsAg, anti-HBs, and anti-HCV assays were conducted using the chemiluminescence methodand HBV DNA, HCV RNA and HCV genotyping tests were conducted using real-time polymerase chain reaction. The data wasretrospectively evaluated.Results: Of 345 patients undergoing hemodialysis, 211 (61.2%) were male and 134 (38.8%) were female. The mean ageof the patients was 62 (15–96) years. Moreover, 0.9% (n = 3) of patients were HBsAg positive and 4.3% (n = 15) wereanti-HCV positive. Three patients with HBsAg positivity were also HBV DNA positive. Of the 15 patients who were antiHCV positive, 12 were also HCV RNA positive. Of these, eight patients had the HCV genotype 1b and four patients hadthe genotype 4. Anti-HBs seropositivity was detected in 65.8% of patients. The highest Anti-HBs seropositivity rate wasobserved in patients aged <40 years (76%) and the difference between age groups was statistically significant (p = 0.002).Conclusion: In our study, the prevalence of HBsAg seropositivity in patients undergoing hemodialysis (0.9%) was lower than thatreported by the Turkish Society of Nephrology (2.65%). This difference may arise from the high anti-HBs seropositivity rate. Conversely,the prevalence of anti-HCV seropositivity (4.3%) was similar to the mean prevalence in Turkey (4.2%). Infection prevention measuresagainst viral hepatitis should be strictly implemented, especially in hemodialysis units
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q Değeri
Scopus Q Değeri
Cilt
26
Sayı
12
