Altay, Cetin MuratTopcuoglu, Osman MelihAlpar, AyhanKüçükay, Murat BülentKüçükay, FahrettinTemel, Tuncer2024-09-292024-09-2920181303-6629https://search.trdizin.gov.tr/tr/yayin/detay/298657https://hdl.handle.net/20.500.14619/11901Background and Aims: To evaluate the safety and efficacy of transhepaticportal vein embolization with Embosphere, Gelfoam, and Amplatzervascular plug II before extended hepatectomy in patients withmetastatic liver disease. Materials and Methods: Between January2008 and October 2014, patients with metastatic liver disease, whowere treated with transhepatic endovascular portal vein embolizationbefore extended hepatectomy to increase the future remnant liver volume,were retrospectively evaluated. Multidetector computed tomographywas utilized before and after the hepatectomy to calculate thefuture remnant liver volume. Ipsilateral portal vein embolization wasperformed in all patients with a microspheric embolic agent (Embosphere,700–900 µm), gelatin foam (Gelfoam), and Amplatzer vascularplug II. Primary outcome measures are the increase in the percentageof the future remnant liver volume, procedure-related mortality andmorbidity, and both technical and clinical success rates. Results: Fourteen(78%) right portal vein and 4 (22%) left portal vein embolizationswere performed in a total of 18 patients (12 men and 6 women) witha mean age of 48±10.1 years (range, 32 to 59 years). The mean increasein the future remnant liver volume at 6 weeks was 41.6±6.7%(range, 35% to 45%), which was sufficient for extended hepatectomy,and the clinical success rate was 100%. The technical success rate was100%, and there was no procedure-related mortality. A self-limitedsubcapsular hematoma occurred in one patient (5%). There was norecanalization of embolized portal veins during follow-ups. Conclusion:Transhepatic portal vein embolization with Embosphere, Gelfoam, andAmplatzer vascular plug II before extended hepatectomy in patientswith metastatic liver disease, is a safe and effective procedure.eninfo:eu-repo/semantics/openAccessGastroenteroloji ve HepatolojiArticle3713329865717