Yaman, Mehmet EmrahAvci, IzzetAtila, Nihal EfeAtila, AlptugKayili, Haci MehmetSalih, Bekir2024-09-292024-09-2920210732-83031532-2327https://doi.org/10.1080/07328303.2021.2009502https://hdl.handle.net/20.500.14619/5670Seasonal allergic rhinitis (SAR) is an inflammatory process. In this pilot study, matrix assisted laser desorption ionization-mass spectrometry (MALDI-MS)-based analyses were conducted to investigate the effects of SAR on serum N-glycome in a small dataset (n = 10 for both SAR patients and controls). It was detected that two N-glycan compositions (H6N5E2L1 and H6N5E1L2) were down-regulated in SAR patients. Additionally, five tri-antennary N-glycan traits, including both galactosylated and sialylated (A3GS and A3GL) and non-fucosylated (A3F0GE, A3F0GL, A3F0GS) ones, were decreased. Furthermore, three high-antennary and fucosylated N-glycan traits (A3F, A3EF and A4F) were increased in SAR patients compared to controls.eninfo:eu-repo/semantics/closedAccessGlycomicsMALDI-TOF-MSmass spectrometryseasonal Allergic rhinitis (SAR)serum N-glycosylationArticle10.1080/07328303.2021.20095022-s2.0-851208719432826Q426940WOS:000725432500001Q3