A Comparative Study on DNA Binding Properties of 2,10,16,24-Tetrakis 4-(4-hydroxyphenyl)-1-phenylethyl) phenoxy)-Substituted Co(II) and Mg(II) Phthalocyanine Compounds

Arslantas, AliAgirtas, Mehmet Salih2024-09-292024-09-2920172365-6549https://doi.org/10.1002/slct.201701224https://hdl.handle.net/20.500.14619/3743In this study, DNA binding properties of 2,10,16,24-tetrakis4-(4-hydroxyphenyl)-1-phenylethyl)phenoxy)phthalocyaninato Co(II) and Mg(II) compounds were analyzed. CT-DNA was used to determine DNA binding properties of Co(II) (4) and Mg(II) (5) phthalocyanine compounds. The DNA binding properties of compounds 4 and 5 were investigated using electronic absorption titration, fluorescence spectroscopy, cyclic voltammetry, thermal denaturation study, electrophoresis and viscosity measurements in Tris-buffer (pH 7.0). The results indicated that Co(II) and Mg(II) phthalocyanine compounds have strong affinity for CT-DNA through intercalation.eninfo:eu-repo/semantics/closedAccessCalf thymus DNACyclic voltammetryDNA-bindingPhthalocyanine compoundsUV/ Vis. spectroscopyA Comparative Study on DNA Binding Properties of 2,10,16,24-Tetrakis 4-(4-hydroxyphenyl)-1-phenylethyl) phenoxy)-Substituted Co(II) and Mg(II) Phthalocyanine CompoundsArticle10.1002/slct.2017012242-s2.0-85041810872866527Q286612WOS:000416746900061Q3