Alshemary, Ammar Z.Muhammed, YasserSalman, Nader A.Motameni, AliGurbuz, Riza2024-09-292024-09-2920220862-54681804-5847https://doi.org/10.13168/cs.2022.0040https://hdl.handle.net/20.500.14619/6633The purpose of this study is to synthesize and characterize the mesoporous nanostructure of Hydroxyapatite (HA), evaluate the impact of the addition of sulphate ions (SO42-) on the microstructure properties of HA, and assess the ability of the prepared materials to be used as a carrier for Bovine serum albumin (BSA) protein. This study successfully synthesized 0.07 mole of SO42-substituted HA using the reflux microwave-assisted wet precipitation method and fully characterized it using modern techniques. In particular, XRD, XPS, Raman, FESEM, and BET techniques were used to explore the micro-structure properties of materials. The results shows that the addition of SO42-ions amplified the lattice parameters and surface area of HA, and the particles shape was changed from semi-spherical to rod like shape. Adsorption and desorption of protein molecules were evaluated using BSA protein for 24 h at 37 degrees C. BSA loading capacity and release behaviours were significantly improved with the incorporation of SO42-ions. The SO4- HA materials hold a promising future for being used as a carrier for protein molecules.eninfo:eu-repo/semantics/openAccessHydroxyapatiteSulphateCharacterizationsAdsorption and desorptionProteinArticle10.13168/cs.2022.00402-s2.0-851403420484524Q344766WOS:000867410800001Q4