Saud, A. NajahKoc, ErkanOzdemir, Olcay2024-09-292024-09-2920230272-88421873-3956https://doi.org/10.1016/j.ceramint.2022.11.093https://hdl.handle.net/20.500.14619/4479Melt-derived route was used to prepare modified bioactive glass-ceramic based on the 45S5 composition with the same network connectivity. Their phase composition, sinterability, and bioactivity were studied. A modified composition was proposed using potassium tetraborate (K2B4O7) to reduce the melting temperature during manufacture. The phase composition and the bioactivity was determined by X-ray diffraction and Fourier transform infrared spectroscopy. Furthermore, the antibacterial properties were evaluated against Enterococcus faecalis. The result shows that glass-ceramics already had P-O and C-O bond functional groups on day 2. These bonds are responsible for the creation of the HCA layer. Scanning electron microscopy (SEM) pictures and Energy Dispersive X-ray Spectroscopy (EDX) investigations showed that, after being immersed in SBF solution, a layer of hydroxyapatite (HA) formed on both BG surfaces on day 2 and that by day 21, HCA cluster crystals had developed. Inductively coupled plasma-optical emission spectroscopy metrics of ionic release from the prepared glass-ceramic, mainly calcium and phosphorus ions in SBF solution, revealed that HCA formation occurred on both BG surfaces, which correlated to the increasing pH within 2 days of incubation; furthermore, it exhibited good antibacterial behavior against the Enterococcus faecalis.eninfo:eu-repo/semantics/closedAccessBioactive glassEutectic reactionMelt-quenchingEnterococcus faecalisHydroxyapatiteArticle10.1016/j.ceramint.2022.11.0932-s2.0-8514277469092786Q1926849WOS:000946143400001Q1