Avciküçük, H.Dülger, D.Aydin, F.Sari, Ü.S.2024-09-292024-09-2920220377-9777https://doi.org/10.5505/TurkHijyen.2022.67355https://search.trdizin.gov.tr/tr/yayin/detay/1126044https://hdl.handle.net/20.500.14619/8798Objective: Viral hepatitis and human immunodeficiency virus (HIV) infections are important health problems in our country as well as all over the world. We aimed to investigate the distribution of seropositivity of HBsAg, anti-HBs, anti-HCV and anti-HIV according to years, genders and age groups in patients who applied to our hospital. Methods: Results of HBsAg, anti-HBs, anti-HCV and anti-HIV tests performed during 2015-2019 in our hospital were reviewed retrospectively. 77,562 serum samples were studied for HBsAg, 45,045 for anti-HBs, 73,223 for anti-HCV and 71,061 for anti-HIV of a total of 266,891 samples. The tests were analysed using chemiluminescent microparticle immunoassay (Architect i 1000, Abbott, USA) and electro-chemiluminescence immunoassay (Cobas 6000,Roche Diagnostic GmbH, Germany) methods. Data were collected from the database of our hospital. Data were analyzed using the SPSS software ver. 24.0. Chi-Square (?2) analysis and Fisher’s Exact test were used for comparison of categorical variables. The p<0.05 was considered statistically significant.Results: HBsAg, antiHBs, anti-HCV and anti-HIV positivity were 2.3 % (1,808/77,562), 46.6% (20,975/45,045), 0.6% (456/73,223) and 0.05% (35/71,061) respectively. Of the 1,808 patients were positive for HBsAg, 55% were males, 45% were females. Of the 456 anti-HCV positive patients, 63.6% were females and 36.4% were males. When assessed by age groups, HBsAg positivity was found to be the highest in the age group 31-50 (38.1%) and lowest in the age group ? 18 (0.6%). Anti-HCV positivity was found to be the highest in the age group ?65 (32%) and lowest in the age group ? 18 (2%). All patients who were found to be anti-HIV positive were male and the highest positivity rate was between the ages of 19-30. Conclusion: Our HBsAg, anti-HBS, anti-HCV and anti-HIV results were found to be similar with the country statistical data. There was significant difference in the seropositivity of HBsAg (p<0,001), anti-HCV (p<0,05) and anti-HIV (p<0,001) during the measurement period. © 2022,Turk Hijyen ve Deneysel Biyoloji Dergisi. All Rights Reserved.eninfo:eu-repo/semantics/openAccessHepatitis b virusHepatitis c virusHivSeropositivitySeroprevalenceArticle10.5505/TurkHijyen.2022.673552-s2.0-851400076404083Q4397112604479