Cesarz-Andraczke, KatarzynaStaszuk, MarcinTuncay, TanselWozniak, AnnaSmok, WeronikaTuncay, Badegul2024-09-292024-09-2920242045-2322https://doi.org/10.1038/s41598-024-69956-6https://hdl.handle.net/20.500.14619/5504This study used the dip-coating method to develop a new biocompatible coating composed of polylactide (PLA) and casein for ZnMg1.2 wt% alloy implants. It evaluated its impact on the alloy's degradation in a simulated body fluid. After 168 h of immersion in Ringer's solution, surface morphology analysis showed that the PLA-casein coatings demonstrated uniform degradation, with the corrosion current density measured at 48 mu A/cm2. Contact angle measurements indicated that the average contact angles for the PLA-casein-coated samples were below 80 degrees, signifying a hydrophilic nature that promotes cell adhesion. Fourier-transform infrared spectroscopy (FTIR) revealed no presence of lactic acid on PLA-casein coatings after immersion, in contrast to pure PLA coatings. Pull-off adhesion tests showed tensile strength values of 7.6 MPa for pure PLA coatings and 5 MPa for PLA-casein coatings. Electrochemical tests further supported the favorable corrosion resistance of the PLA-casein coatings, highlighting their potential to reduce tissue inflammation and improve the biocompatibility of ZnMg1.2 wt% alloy implants.eninfo:eu-repo/semantics/openAccessSurface ModificationCorrosionPerspectivePerformanceAcidArticle10.1038/s41598-024-69956-62-s2.0-85201416295139147799Q114WOS:001292157300006N/A