Arslantas, AliAgirtas, Mehmet Salih2024-09-292024-09-2920182365-6549https://doi.org/10.1002/slct.201800172https://hdl.handle.net/20.500.14619/3746In this study, 2(3), 9(10), 16(17), 23(24)-tetrakis 2((4-phenoxyphenyl) diazeylbenzoic acid)phthalocyaninato zinc (II) compound was chosen to study DNA binding activities. The binding activities of zinc (II) phthalocyanine compound bearing 2(3),9(10), 16(17), 23(24)-tetrakis 2((4-Phenoxyphenyl) diazeylbenzoic acid) ligand with Calf Thymus (CT)-DNA was investigated using absorption titration, fluorescence spectroscopy, cyclic voltammetry and thermal melting profile in a Tris-HCl buffer system at pH7.0. In addition to these methods, gel electrophoresis and viscosity measurements were also carried out to determine DNA binding activities with compound 6 in a buffer solution. The results indicated that compound 6 interacts with CT-DNA through partial intercalation binding mode.eninfo:eu-repo/semantics/closedAccessAbsorption spectroscopyCyclic voltammetryDNA bindingMetallo phthalocyaninesArticle10.1002/slct.2018001722-s2.0-8504212504417606Q217553WOS:000425012500022Q3