Karagun, EbruErgin, CanBaysak, SevimErden, GonulAktas, HabibullahEkiz, Ozlem2024-09-292024-09-2920161642-395Xhttps://doi.org/10.5114/pdia.2016.59507https://hdl.handle.net/20.500.14619/7688Introduction: Vitiligo is a common acquired pigmentary skin disorder. Vitamin D is responsible for skin pigmentation, increases tyrosinase activity and melanogenesis, and exhibits immunoregulatory functions. Low levels of vitamin D are associated with many autoimmune diseases, including systemic lupus, diabetes mellitus, rheumatoid arthritis, multiple sclerosis and alopecia areata. Few reports have evaluated serum vitamin D levels in vitiligo patients, and their results are conflicting. Aim: To evaluate serum vitamin D levels of vitiligo patients and compare the results with controls. Material and methods: In total, 50 vitiligo patients and 47 controls were enrolled in the study. Vitamin D levels were measured from blood samples. Group comparisons were performed using appropriate statistical methods. Results: The patients had lower serum vitamin D levels than the controls, but this difference was not significant (p = 0.570). Conclusions: It remains unknown whether vitamin D deficiency causes vitiligo. Larger controlled studies are required to prove whether low circulating vitamin D is a causative factor in vitiligo.eninfo:eu-repo/semantics/openAccessvitiligovitamin Dautoimmune diseasesetiopathogenesisArticle10.5114/pdia.2016.595072-s2.0-84983436727302427605903Q330033WOS:000382410900011Q3