Yazar "Çekmen, Bora" seçeneğine göre listele
Listeleniyor 1 - 7 / 7
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Akut aort diseksiyonu tanısında kullanılabilecek kan parametreleri(2024) Bildik, Büşra; Yilmaz, Gökhan; Atis, Seref Emre; Çekmen, BoraAmaç: Akut aort diseksiyonu yüksek mortalite ve morbiditeye sahip bir hastalıktır. Oldukça geniş semptomlara neden olması sebebiyle tanısı sıklıkla atlanmakta veya akut koroner sendom, gastrointestinal hastalıkları veya serebrovasküler hastalıklarla karıştırılabilmektedir. Çalışmamızda, aort diseksiyonu tanısı alan hastalarda bakılan kan parametrelerinin tanıyı belirlemedeki etkinliğini saptamayı hedefledik. Yöntemler: Çalışmamız retrospektif, kesitsel bir çalışma olarak planlandı. Çalışmamıza üçüncü basamak bir acil servise göğüs ağrısı şikâyeti ile başvuran ve aort diseksiyonundan şüphe edilip, bilgisayarlı toraks ve abdomen anjiografisi (BTAA) çekilen hastalar dâhil edildi. Çalışmaya alınan hastalar iki gruba ayrıldı ve BTAA raporunda aort diseksiyonu saptanıp saptanmamasına göre aort diseksiyonu olanlar “hasta grubu” ve aort diseksiyonu saptanmayanlar ise “kontrol grubu” olarak belirlendi. Hastalara ait yaş, cinsiyet gibi demografik verilerle birlikte, tam kan parametreleri (lökosit, lenfosit, nötrofil, platelet sayıları), C-reaktif protein (CRP), kreatinin değerleri kaydedildi. Bulgular: Çalışmaya 64 hasta dâhil edildi. Çalışmaya alınan hastaların yaş ortalaması 61,48±14,49 olarak saptandı. Hastalar ve kontrol grubu karşılaştırıldığında, aort diseksiyonu olan grubun yaş ortalaması 56,96±10,37, kontrol grubun ise 64,20±15,98 olarak saptandı. Aort diseksiyonu olan grubun yaş ortalaması kontrol grubuna göre istatistiksel olarak anlamlı bir şekilde daha düşüktü (p=0,032). Aort diseksiyonu olan grubun platelet sayısı 199 109/L [162-260], kontrol grubunun ise 260 109/L [348-223] olarak saptandı (p=0,003). Platelet değeri için yapılan ROC analizinde, değer 199 109/L olarak alındığında, aort diseksiyonu için duyarlılık %50,0 (pozitif prediktif değeri =2,5), özgüllük %80,0 (negatif prediktif değeri =0,63) olarak belirlendi (AUC= 0,725 [0,597-0,853], p=0,003). Sonuç: Platelet sayısı ve yaş, aort diseksiyonu tanısında bağımsız risk faktörleridir. Düşük platelet sayısı seviyeleri aort diseksiyonu tanısını destekler.Öğe C-reaktif protein/albumin oraninin ileus tipini ve prognozu belirlemedeki yeri(2022) Çekmen, Bora; Kolcu, GirayAmaç Son zamanlarda, sistemik inflamasyon ve beslenme durumu için bu belirteçlerin bir kombinasyonu olan CRP/albümin oranı, enfeksiyon, malignite ve diğer hastalıkları olan hastalarda bağımsız bir prognostik belirteç olduğu saptanmıştır. Çalışmamızda, ileus tanısı ile hastaneye yatan hastalarda başvuru anındaki CRP-albumin oranının ileus nedenini ve prognozu tahmin etmedeki etkinliğini araştırmayı amaçladık. Gereç ve Yöntem Çalışmaya acil servise başvuran ve sonrasında ileus tanısı alan 18 yaş üstü hastalar alınmıştır. Hastaların demografik özellikleri, laboratuvar parametreleri, cerrahi müdahale geçirip geçirmedikleri, yatış süreleri ve hastane içi mortaliteleri belirlenmiştir. Etiyolojisine göre paralitik veya mekanik olarak ayrılmıştır. CRP/ albümin oranı (CAR) hesaplanmış, CAR’ın ileus nedeni ve mortaliteyi tahmin etmedeki etkisi araştırılmıştır. Bulgular Toplam 116 hasta araştırıldı. Hastaların 72 (%62,1)’si erkek, yaş ortalaması 65,12’di. 81 (%69,8)’inde mekanik ileus saptandı. İleus tiplerine göre mekanik ileus hastalarının %66,7’si medikal tedavi alırken, paralitik ileusta%97,1’i medikal tedavi aldığı saptandı. Paralitik ileus hastalarında tedavi tercihi daha fazla orandı medikaldi (p<0,001). Mekanik ileus olan hastaların CAR değeri 3,72, paralitik ileus olanların ise 5,77 saptandı. (p=0,046) Bütün ileus hastalarında CAR, WBC, yatış süresi, nötrofil ve lenfosit sayısı, CRP değerinin incelendiği lojistik regresyon analizinde hiçbir parametrenin mortalite için bağımzsız bir gösterge olmadığı ortaya çıkmıştır. Sonuç CAR değeri ileus tipini belirlemede faydalı olabilir. İleus hastalarında mortalite tahmininde yararlı görülebilirken bağımsız bir gösterge değildir.Öğe Comparison of demographic and laboratory data of young and elderly patients who deceased due to covid-19(2022) Çekmen, BoraIntroduction: Differences between young and elderly patients who deceased due to COVID-19 require further elucidation. The present study aimed to compare the differences between young and elderly patients who died from COVID-19. Material and Method: In this single-center cross-sectional study, patients included who had been diagnosed with COVID-19 and had died in the course of hospital follow-up. The following data were recorded. Demographic characteristics of the patients, date of diagnosis, length of diagnosis to death, the first place of hospitalization, duration of hospitalization at the clinical service and intensive care unit, blood parameters. Patients included in the study were divided into 2 groups, i.e., patients aged <65 and ?65 years, and the relationship between the study data and these two groups were examined. Results: We included 369 patients. Prevalence of comorbid chronic diseases was significantly higher in the ?65 years group (81.3% vs. 90.1%, p = 0.034). Prevalence of hypertension and chronic obstructive pulmonary disease was higher in the ?65 years group (respectively, 72% vs. 84.4%, p = 0.013; 10.7% vs. 30.6%, p < 0.001). Intergroup comparison of laboratory parameters indicated that alanine aminotransferase and lactate dehydrogenase levels were higher in the <65 years group (respectively, p = 0.004; p = 0.020), whereas the creatinine levels were higher in the ?65 years group (p < 0.001). Conclusion: This study captured the comorbidities, laboratory parameters, and duration of hospitalization of young and elderly patients, who died due to COVID-19. In the light of the study data, there was no significant intergroup difference.Öğe Did the COVID-19 pandemic period increased suicide attempts in society?(2023) Uzun, Ahmet; Çekmen, BoraAim: To analyze the influence of the COVID-19 pandemic and quarantine on suicidality. Material and Methods: This study was conducted on patients over the age of 15 who were suicidal and admitted to the emergency department of our hospital. The patients were disunited into two groups: pandemic group covering the period from March 11, 2020 to March 11, 2021, the former being the date when the first patient of COVID-19 was identified in Turkey, and pre-pandemic group covering the period from March 11, 2019 to March 10, 2020. Results: The study was conducted with a total of 271 patients. The number of suicide attempts in the first time period (March-AprilMay-June) was 42 (28.4%) in the pandemic group and 16 (13.0%) in the pre-pandemic group, with significantly higher numbers in the pandemic group for the first time period (p=0.008). The distribution in the remaining second and third time periods was similar to those in the previous year. Conclusion: Compared to the pre-pandemic period, suicide attempts significantly increased in the early stages of the pandemic as the first case was identified in Turkey and the lockdown was imposed because of the increasing cases. In the later stages of the pandemic, there was no obvious change in the amount of suicide compared to previous periods.Öğe Evaluation of brain oxygenation by near infrared spectroscopy in healthcare professionals using surgical and ffp2/n95 masks(2022) Bozan, Öner; Atıs, Seref Emre; Çekmen, Bora; Karakısa, Halit; Karaaslan, Edip Burak; Ferhatlar, Mehmet Esat; İslam, Mehmet MuzafferAim: The present study aimed to detect changes in brain oxygenation associated with the use of surgical and FFP2/N95 masks using the near infrared spectroscopy (NIRS) method. Material and Methods: Volunteers wearing surgical masks were asked to sit upright for 30 minutes. Cerebral oxygen saturation values were measured at the 1st, 5th, and 30th minutes (group 1). The mask wearers were requested to return at the same time on the day following this procedure. In group 2, serial cerebral oxygen saturation values (SpO2) were obtained at the same time intervals as in group 1, but while the subjects were wearing FFP2/N95 masks. Results: A statistically significant difference was found between the groups in the comparison of the values measured using NIRS at the 1st, 5th, and 30th minutes in group 1. According to the post-hoc analysis, this difference was due to discrepancies in NIRS measurements at the 1st minute and 30th minute and at the 5th minute and 30th minute. No statistically significant difference was found between the groups in the comparison of the values measured using NIRS at the 1st, 5th, and 30th minutes in group 2. Conclusion: Neither surgical nor FFP2/N95 masks caused a clinically significant negative difference in brain oxygenation.Öğe Evaluation of routine coagulation testing requirements in patients with severe epistaxis(2021) Çekmen, Bora; Bozan, Öner; Atıs, Seref Emre; Ünver, Sevilay Sema; Kokulu, Kamil; Kalkan, AsimAim: There are studies about coagulation parameters are not required in the management of epistaxis. The aim of the present study was to investigate whether or not coagulation tests are required and its relationship with medications in severe epistaxis cases that require intervention. Material and Method: The patients above 16 years who had presented to emergency department due to epistaxis, who had undergone anterior/posterior nasal packing or electro-cautery to the nasal mucosa were included the study. The demographic characteristics, blood count, coagulation test, anti-platelet and anti-coagulant medications, the procedures carried out for stopping bleeding, whether reversal treatment or blood transfusion was needed were recorded. Results: A total of 469 patients, it was found that coagulation parameters had been tested in 141(30.2%). While PT, aPTT and INR values of the anti-coagulant using patients were significantly higher(p<0.001, p=0.003, p<0.001, respectively), the platelet and hemoglobin values were not found to be associated with anti-platelet drug and anti-coagulant use(p=0.304, p=0.098, respectively). The patients were allocated to two groups as those any parameter of whom was impaired or not. While a significant difference was found between the groups with regard to hemoglobin values(p=0.006), no patients were determined to need reversal treatment or hemoglobin replacement.Conclusion: Routine coagulation testing is not required for patients who have epistaxis that cannot be stopped with conservative methods and who are using anti-platelet drugs as it does not lead to a difference in treatment. Coagulation tests may not be performed in patients who use anti-coagulants based on the results.Öğe Role of eosinophil count and percentage in chronic obstructive pulmonary disease exacerbation: a retrospective observational study(2022) Gürlevık, Ercan; Cander, Basar; Çekmen, Bora; Özdemir, SerdarAim: To reveal the role of eosinophil count and percentage evaluated at the time of presentation in patients hospitalized with the exacerbation of chronic obstructive pulmonary disease (COPD). Material and Methods: In this study, the data of patients with a diagnosis of the exacerbation of COPD, who presented to the emergency department, and admitted to the general internal medicine ward, were retrospectively analyzed. The relationship of eosinophil count and ratios with the length of hospital stay and intensive care requirement was investigated.The Spearman correlation analysis was used for investigating correlation between parameters and outcome. Results: Of the study population, 39.7% were female and 60.3% were male. The ages of the participants ranged from 25 to 94 years, with a median value of 76 years. There was no significant correlation between the length of stay in ward and eosinophil count and percentage (rho=-0.148, p=0.066 and p=0.074, rho=-0.143, respectively) (Spearman correlation test). The group admitted to the intensive care unit had a significantly higher eosinophil count and percentage of eosinophils than the group that did not require intensive care (0.81(Inter Quarter Range (IQR):0.41-1.31) versus 1.32 (IQR:0.83-1.43) p=0.042 and 1.0 (IQR:0.81-1.21) versus 1.42 (IQR:1.02-1.64), p=0.018, respectively) (Mann Whitney U test). Conclusion: There was no correlation between a high eosinophil count and percentage and the length of hospital stay. However, the number and percentage of eosinophils were significantly higher among the patients requiring intensive care.
