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    Anesthesia mumps resulting in temporary facial nerve paralysis after the auditory brainstem implantation in a 3-year-old child
    (Elsevier Ireland Ltd, 2014) Ozdek, Ali; Bayir, Omer; Isik, Murat Eray; Tatar, Emel Cadalli; Saylam, Guleser; Korkmaz, Hakan
    An acute transient sialadenitis of the major salivary glands in the early postoperative period is called 'anesthesia mumps'. It has been reported in different surgical procedures especially in neurosurgical procedures. Anesthesia mumps develops very fast after the extubation period but it usually regresses with no sequelae within a few hours. However, sometimes serious complication can occur such as respiratory distress. In this report, we present a 3-year-old girl with an anesthesia mumps and facial palsy occurring after successful auditory brainstem implantation and we discuss the cause and the management of this rare complication in this report. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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    Hearing restoration in NF2 patients and patients with vestibular schwannoma in the only hearing ear: report of two cases
    (W B Saunders Co-Elsevier Inc, 2014) Ozdek, Ali; Bayir, Omer; Donmez, Teoman; Ozisik, Pinar; Sahin, Mustafa; Tulgar, Meltem; Tatar, Emel Cadalli
    Objective: To explore audiologic outcome of auditory brain stem implantation (ABI) and cochlear implantation (CI) in NF2 patients and patients with vestibular schwannoma (VS) in the only hearing ear. Patients and methods: Study includes retrospective analysis of 2 cases. One is totally deaf patient due to NF2, and the other one is totally deaf due to VS development in only hearing ear. Tumor was removed by retrosigmoid approach in NF2 patient and ABI was performed simultaneously. For the VS in only hearing ear case, tumor was removed by translabyrinthine approach and CI was performed simultaneously. Results: ABI patient showed quite well outcome during the 15 months of follow-up. She has 25 dB hearing threshold at speaking frequencies. She developed open set speech discrimination with 87.5% word discrimination score, and 70% sentence discrimination score. She uses device daily manner, she can use telephone. For CI patient, outcome is not perfect but satisfactory. She couldn't develop open set speech discrimination during the 18 months of follow-up. She has 67% the disyllabic words recognition score (close set). She is daily user of device. CI improves quite well lip reading. Conclusion: ABI and CI are the two options to restore hearing in VS caused deafness. We advocate giving every effort to preserve cochlear nerve during the VS resection and place CI simultaneously. However if it is not possible to preserve cochlear nerve during surgery, ABI is also a good alternative for hearing restoration. (C) 2014 Elsevier Inc. All rights reserved.
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    Interscapular Pharyngocutaneous Fistula: An Extreme Complication of Cervical Stabilization Surgery
    (Turkish Neurosurgical Soc, 2013) Korkmaz, Hakan; Saylam, Guleser; Bayir, Omer; Cadalli Tatar, Emel; Ozdek, Ali
    Pharyngeal and esophageal perforations are rare during cervical spine surgery but can cause significant morbidity. Pharyngeal or eosephageal perforations can occur by several mechanisms and the management of pharyngeal or eosephageal perforation's treatment may become difficult. We report a 41-year-old paraplegic man with an interscapular pharyngocutaneous fistula secondary to cervical vertebral surgery. The diagnosis of posterior fistula was delayed for several months as it was an extremely rare complication. We explored the anterior neck and repaired the perforation on the right pyriform sinus primarily. The fistula tract on the back of the patient was completely healed and the patient started oral feeding in the second week after surgery.
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    Permanent central diabetes insipidus as a complication of sphenoid sinus mucocele
    (W B Saunders Co-Elsevier Inc, 2014) Saylam, Guleser; Bayir, Omer; Girgin, Derya; Arslan, Muyesser Sayki; Tatar, Emel Cadalli; Ozdek, Ali; Delibasi, Tuncay
    Although mucocele is a benign lesion, its unavoidable expansions may result in irreversible damages in adjacent organs. In spheno-ethmoid mucoceles which are extremely rare, this condition may cause more severe problems. Central diabetes insipidus, developed secondary to sphenoid sinus mucocele, was detected in a 54-year-old male patient, who underwent endoscopic sinus surgery 2 times due to nasal polyposis. Endoscopic sphenoid mucocele marsupialization was performed to the patient, but despite partial regression in the 1-year follow up, complete recovery was not observed. (C) 2014 Elsevier Inc. All rights reserved.
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    Vestibular Evoked Myogenic Potential Responses in Behcet's Disease
    (Aves, 2012) Bayir, Omer; Comoglu, Selim Selcuk; Ozdek, Ali; Aytac, Emrah; Guven, Hayat; Ozdal, Muge Pinar; Korkmaz, Hakan
    Objective: To evaluate the vestibular evoked myogenic potentials responses in patients with Behcet's disease. Materials and Methods: Thirty-three patients (66 ears) with the diagnosis of Behcet's disease and 33 (66 ears) age and sex matched healthy volunteers were enrolled in the study. Logon type stimulus; 500 Hz frequency at an intensity of 120 dB HL with a 4/s stimulation rate was delivered to elicite the VEMP responses. The sternocleidomastoid muscle was chosen as the target to record the VEMPs. During the recording period subjects were in supine position with head elevation and simultaneous binaural acoustic stimulations were used. Results: The response rate of p1n1 wave was 69.7 % for Behcet group and 89.4% for the control group (X2, p= 0.009). For Behcet group, the mean latencies of p1 and n1 were 13.7 +/- 1.2 ms and 19.7 +/- 1.4 ms, the mean amplitude of p1n1 wave was 12.2 +/- 5.9 mu V. For control group, these values were 14.2 +/- 1.3 ms; 20.8 +/- 2.1 ms and 14.1 +/- 6.1 mu V, respectively. Although there were no significant differences between the two groups with respect to p1 latency and p1n1 amplitude, n1 latencies were significantly shorter in Behcet group. Conclusion: This preliminary report notify that in Behcet's disease, the VEMP response rate is lower and n1 latency was shorter than the healthy subjects.
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    Vestibular evoked myogenic potential responses in obstructive sleep apnea syndrome
    (Springer, 2015) Mutlu, Murad; Bayir, Omer; Yuceege, Melike B.; Karagoz, Tugba; Firat, Hikmet; Ozdek, Ali; Akin, Istemihan
    Obstructive sleep apnea syndrome (OSAS) provokes oxidative stress and ischemia, which affects the central nervous system. The degeneration of neurons in the brainstem due to periodic hypoxia can be evaluated by vestibular and audiologic tests. The objective of this study is to determine brainstem damage in severe OSAS patients with the help of vestibular evoked myogenic potential (VEMP) responses. Prospective, randomize, double-blind. Research-training hospital. We compared cervical vestibular evoked myogenic potential (cVEMP) responses between severe OSAS patients and a control group. 54 patients were included and divided into the OSAS group, with severe OSAS (apnea-hypopnea index, AHI > 70), and a control group with snoring without OSAS (AHI < 5). Both groups underwent cVEMP. Bilateral recordings with simultaneous binaural logon stimulations were used during VEMP recordings. The existing p1n1 and n2p2 responses, p1, n1, n2, and p2 latencies and amplitudes, and p1n1 and n2p2 intervals were measured. Statistically significant differences were revealed between patients and controls for the response rate of the p1n1, n2p2 and p1n1, n2p2 amplitudes. There were no significant differences between the two groups with respect to the latencies of p1, n1, n2 and p2, or the p1n1 and n2p2 intervals. The VEMP response rate was lower in severe OSAS patients, and all amplitudes were shorter than in healthy subjects. VEMP recordings in severe OSAS subjects demonstrates abnormalities in brainstem pathways. It appears that brainstem damage in severe OSAS can be detected by cVEMP recordings.
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    Vestibular-evoked myogenic potentials, clinical evaluation, and imaging findings in multiple sclerosis
    (Springer-Verlag Italia Srl, 2014) Guven, Hayat; Bayir, Omer; Aytac, Emrah; Ozdek, Ali; Comoglu, Selim Selcuk; Korkmaz, Hakan
    Vestibular-evoked myogenic potentials (VEMP), short-latency electromyographic responses elicited by acoustic stimuli, evaluate the function of vestibulocollic reflex and may give information about brainstem function. The aim of the present study is to evaluate the potential contribution of VEMP to the diagnosis of multiple sclerosis (MS). Fifty patients with MS and 30 healthy control subjects were included in this study. The frequency of VEMP p1-n1 and n2-p2 waves; mean p1, n1, n2, and p2 latency; and mean p1-n1 and n2-p2 amplitude were determined. The relation between clinical and imaging findings and VEMP parameters was evaluated. The p1-n1 and n2-p2 waves were more frequently absent in MS than in control subjects [p1-n1 wave absent: MS, 25 (25 %) ears; control, 6 (10 %) ears; P a parts per thousand currency sign 0.02] [n2-p2 wave absent: MS, 44 (44 %) ears; control, 7 (12 %) ears; P a parts per thousand currency sign 0.001]. The mean p1-n1 amplitude was lower in MS than in control subjects (MS, 19.1 +/- A 7.2 mu V; control, 23.3 +/- A 7.4 mu V; P a parts per thousand currency sign 0.002). A total of 24/50 (48 %) MS patients had VEMP abnormalities (absent responses and/or prolonged latencies). VEMP abnormalities were more frequent in patients with than without vestibular symptoms (P a parts per thousand currency sign 0.02) and with brainstem functional system score (FSS) a parts per thousand yen1 than FSS = 0 (P a parts per thousand currency sign 0.02). In patients with MS, absence of p1-n1 wave was more frequent in patients with than without vestibular symptoms [absence of p1-n1 wave: vestibular symptoms, 9 (45 %) ears; no vestibular symptoms, 16 (20 %) ears; P a parts per thousand currency sign 0.03] and patients with Expanded Disability Status Scale (EDSS) score a parts per thousand yen5.5 [absence of p1-n1 wave: EDSS a parts per thousand yen5.5, 7 (70 %) ears; EDSS < 5.5, 18 (20 %) ears; P a parts per thousand currency sign 0.001]. Abnormal VEMP may be noted in MS patients, especially those with vestibular symptoms and greater disability. The VEMP test may complement other studies for diagnosis and follow-up of patients with MS.