Yazar "Bozer, Busra Moran" seçeneğine göre listele

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    Bio-properties of Mg-RE alloys: an applied study on cytotoxicity and genotoxicity
    (Taylor & Francis Ltd, 2024) Djebari, Kenza; Turen, Yunus; Elen, Levent; Ahlatci, Hayrettin; Bozer, Busra Moran; Cicek, Bunyamin
    This study presents a comprehensive review of magnesium alloys with rare elements. It discusses Mg-RE alloys and includes an experimental process. Thus, the data obtained by examining Mg-RE alloys provided a better interpretation of the experimental study. In this study's investigation report, Mg-RE alloys were thoroughly analyzed. In the experimental part, the cytotoxic and genotoxic results of the rare elements added to the Mg-Zn-RE master alloy are discussed. Experiments were carried out by adding Nd and Ce to this master alloy in inverse proportions. In cytotoxic data, it was observed that the viability rate in bacteria increased by up to 200%. In addition, significant genotoxic results of Mg-RE alloys were obtained, which are uncommon in the literature. As a result, a new perspective on Mg-RE alloys has been created. Cette & eacute;tude pr & eacute;sente un examen complet des alliages de magn & eacute;sium contenant des & eacute;l & eacute;ments rares. Elle discute des alliages Mg-ER et comprend un proc & eacute;d & eacute; exp & eacute;rimental. Ainsi, les donn & eacute;es obtenues en examinant les alliages Mg-ER ont fourni une meilleure interpr & eacute;tation de l'& eacute;tude exp & eacute;rimentale. Dans le rapport d'investigation de cette & eacute;tude, on a analys & eacute; & agrave; fond les alliages Mg-ER. Dans la partie exp & eacute;rimentale, on discute des r & eacute;sultats cytotoxiques et g & eacute;notoxiques des & eacute;l & eacute;ments rares ajout & eacute;s & agrave; l'alliage m & egrave;re Mg-Zn-ER. On a r & eacute;alis & eacute; des exp & eacute;riences en ajoutant du Nd et du Ce & agrave; cet alliage m & egrave;re en proportions inverses. Dans les donn & eacute;es cytotoxiques, on a observ & eacute; que le taux de viabilit & eacute; des bact & eacute;ries a augment & eacute; jusqu'& agrave; 200%. De plus, on a obtenu des r & eacute;sultats g & eacute;notoxiques significatifs des alliages Mg-ER, qui sont peu communs dans la litt & eacute;rature. Par cons & eacute;quent, on a cr & eacute;& eacute; une nouvelle perspective sur les alliages Mg-ER.
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    Spectral analysis and biological activity assessment of silver doped hydroxyapatite
    (Taylor & Francis Ltd, 2021) Erdem, Umit; Bozer, Busra Moran; Turkoz, Mustafa B.; Metin, Aysegul U.; Yildirim, Gurcan; Turk, Mustafa; Nezir, Saffet
    In this study, the hydroxyapatite biomaterials are produced by the precipitation method and the role of silver doping within the different molar ratios of 2.0, 5.0, and 10.0% are investigated with some fundamental analysis, including powder XRD, SEM, EDS, FTIR, Raman, and material densities. In vitro biocompatibility assessment is conducted with cytotoxicity and agar diffusion tests. Moreover, genotoxicity tests determine whether the biomaterials produced cause the mutations or not. In addition, a hemolytic effect test examines the variation of hemolytic behavior of compounds. Also, the cell migration experiments inspect the influence of silver ion levels in biomaterials on many biological processes. The experimental results reveal that the honeycomb-patterned morphological structures are obtained for all the products. FTIR and Raman analyses reveal that the dramatic changes in the characteristic functional group peaks are obtained with the increment in the amount of silver ions. The experimental parts related to the biocompatibility assessment of the study show that there seems to be deterioration in biocompatibility as the silver ion-doping level increases in the system. To sum up, the ideal doping value for bone tissue engineering applications is found to be 2%.