Yazar "Demir, Demirhan Orsan" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus
    (2024) Yılmaz, Ümit; Burlukkara, Salih; Demir, Demirhan Orsan
    This study was designed to determine the serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus (T2DM). A total of 154 individuals aged 30-60 were included in the study and the participants were divided into three groups: D-ED group (individuals with T2DM and ED) (n=49), ND-ED group (individuals with ED without T2DM) (n=55), and control group (individuals without T2DM and ED) (n=50). The age, BMI, and IIEF-5 score were recorded for all participants. The HDL, LDL, triglycerides, cholesterol, HbA1c and testosterone were determined from the blood taken from the participants, and galanin and relaxin-3 levels were measured in serum samples by ELISA method. The IIEF-5 score of the D-ED group was statistically lower than that of the ND-ED and control groups, and the IIEF-5 score of the ND-ED group was also lower than that of the control group. Serum testosterone levels in the control group were statistically higher than in the D-ED and ND-ED groups. The galanin level of the D-ED group was elevated than the control and ND-ED groups, but the galanin level of the ND-ED group was lower than the control group. The relaxin-3 levels were decreased in the D-ED and ND-ED groups compared to the control group. Galanin levels increased in individuals with T2DM and ED, however decreased in individuals with ED without T2DM. In addition, reduced relaxin-3 level may play a role in the development of ED.
  • Küçük Resim Yok
    Öğe
    Women in urology: Gender differences in urologists' authorship in high impact journals
    (Wiley, 2023) Demir, Demirhan Orsan; Karagoz, Mehmet Ali
    Background The number of women among medical doctors and surgeons continues to rise. However, urology remains one of the least preferred specialties by female physicians, resulting in the inadequate academic representation of female urologists. In this study we examined changes in the representation of female urologists in the journals European Urology (EU) and Journal of Urology (JOU) and investigated in which urology subspecialties female urologists focus their academic studies. Methods Original articles, reviews and case reports published in EU and JOU were included in the study. The analysis was limited to 4 years, starting with 2004 and continuing at 5-year intervals until 2019.The publications were also classified according to urology subspecialty and geographic location. Results In total, 2708 articles were analysed. Overall, women accounted for 9.9% of first authors (267/2708) and 5.9% of senior authors (161/2708).The proportion of female first authors was 8.2% in 2004 and increased to 10.7% in 2009, 10.6% in 2014, and 11.6% in 2019 (P = 0.062). The proportion of female last authors was 7% in 2004 and 5.3%, 6.1%, and 2.5% in 2009, 2014, and 2019, respectively (P = 0.011). Women accounted for a significantly higher proportion of first authors than men in publications related to female and paediatric urology (P = 0.001 and P = 0.002, respectively). Conclusions The increasing number of women urologists worldwide is not reflected in the scientific authorship of female urologists. Multicenter studies focusing on the elimination of gender disparity in academic representation are needed in surgical branches such as urology.