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Öğe Change in transition balance between durable tetragonal phase and stress-induced phase of cobalt surface-layered in Bi-2212 materials by semi-empirical mechanical models(Iop Publishing Ltd, 2023) Erdem, Umit; Yildirim, Gurcan; Turkoz, Mustafa Burak; Ulgen, Asaf Tolga; Mercan, AliThis study has indicated the positive effect of sintering temperature on the mechanical durability, strength, critical stress, deformation degrees, durable tetragonal phase, failure and fracture by fatigue, and mechanical characteristic behavior to the applied test loads for the Co surface-layered Bi-2212 ceramic materials produced by the standard solid-state reaction method. The sintering mechanism has been used as the driving force for the penetration of cobalt ions in the Bi-2212 ceramic matrix. The microindentation hardness test measurements have been performed at the load intervals 0.245 N-2.940 N. The experimental findings have also been examined by the six different semi-empirical mechanical and indentation-induced cracking models. It has been found that all the mechanical performance parameters are improved considerably with increasing the diffusion sintering temperature up to 650 degrees C. On this basis, the Co surface-layered Bi-2212 sample produced at the sintering temperature of 650 degrees C has been observed to improve dramatically the mechanical durability and resistance to the applied test loads as a consequence of the formation of new force barrier regions, surface residual compressive stress regions, and slip systems in the Bi-2212 ceramic system. Similarly, the optimum sintering temperature has extensively enhanced the elastic recovery mechanism, critical stress values, and deformation degree levels, stored internal strain, and crack surface energy through the Bi-2212 ceramic materials. Accordingly, it has been noted that the best sample produced at 650 degrees C is more hardly broken than the other ceramics. Namely, the optimum sintering temperature has decreased the sensitivity to the applied test loads as a result of delaying the beginning of the plateau limit regions. On the other hand, all the mechanism has been found to reverse completely depending on the excess sintering temperature. Lastly, the indentation-induced cracking model has been found to exhibit the closest results to the original Vickers microhardness parameters in the plateau limit regions.Öğe Contribution of vanadium particles to thermal movement of correlated two-dimensional pancake Abrikosov vortices in Bi-2223 superconducting system(Elsevier, 2023) Ulgen, Asaf Tolga; Erdem, Umit; Yildirim, Gurcan; Turkoz, Mustafa Burak; Turgay, TahsinThis article breaks new ground in understanding of variation in the magnetic strength performance, flux pinning and energy dissipation mechanism of polycrystalline bulk Bi1.8Sr2.0Ca2.2Cu3.0Oy (Bi-2223) superconducting materials added with the different vanadium concentration level (0.0 <= x <= 0.30) under the magnetic field strengths applied up to 5 T for the first time. We provide the sophisticated and phenomenological discussions on the magnetoresistivity measurement results in three main sections along the paper. All the findings show that the increase of both the vanadium concentration in the crystal structure and external magnetic field strength damages significantly the magnetic strength performance, vortex dynamics, flux pinning ability and vortex lattice elasticity of bulk Bi-2223 superconducting ceramics. The vanadium addition promotes thermally the movement of correlated two-dimensional (2D) pancake Abrikosov vortices between the in-plane Cu-O-2 layers in the valance band, vortex lattice elasticity, vortex dynamics, distance for interlayer Josephson couplings and flux pinning centers and the theoretical computations confirm the remarkable degradation in the formation of super-electrons in the Bi-2223 crystal system. Thus, the vanadium addition is anticipated to be one of the best selectable materials to examine the differentiation in the thermal movement of correlated 2D Pancake Abrikosov vortices in the bulk Bi-2223 superconducting system. (c) 2022 The Author(s). Published by Elsevier Espana, S.L.U. on behalf of SECV. This is anopen access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/ by-nc-nd/4.0/).Öğe Dentinal tubule occluding capability of nano-hydroxyapatite; The in-vitro evaluation(Wiley, 2018) Baglar, Serdar; Erdem, Umit; Dogan, Mustafa; Turkoz, MustafaIn this in-vitro study, the effectiveness of experimental pure nano-hydroxyapatite (nHAP) and 1%, 2%, and 3% F doped nano-HAp on dentine tubule occlusion was investigated. And also, the cytotoxicity of materials used in the experiment was evaluated. Nano-HAp types were synthesized by the precipitation method. Forty dentin specimens were randomly divided into five groups of; 1no treatment (control), 2specimens treated with 10% pure nano-HAp and 3, 4, 5 specimens treated with 1%, 2%, and 3% F(-)doped 10% nano-HAp, respectively. To evaluate the effectiveness of the materials used; pH, FTIR, and scanning electron microscopy evaluations were performed before and after degredation in simulated body fluid. To determine cytotoxicity of the materials, MTT assay was performed. Statistical evaluations were performed with F and t tests. All of the nano-HAp materials used in this study built up an effective covering layer on the dentin surfaces even with plugs in tubules. It was found that this layer had also a resistance to degradation. None of the evaluated nano-HAp types were have toxicity. Fluoride doping showed a positive effect on physical and chemical stability until a critical value of 1% F-. The all evaluated nano-HAp types may be effectively used in dentin hypersensitivity treatment. The formed nano-HAp layers were seem to resistant to hydrolic deletion. The pure and 1% F(-)doped nano-HAp showed the highest biocompatibility thus it was assessed that pure and 1% F(-)doped materials may be used as an active ingredient in dentin hypersensitivity agents.Öğe Development of modulation, pairing mechanism, and slip system with optimum vanadium substitution at Bi-sites in Bi-2212 ceramic structure(Elsevier Science Sa, 2023) Ulgen, Asaf Tolga; Okur, Semih; Erdem, Umit; Terzioglu, Cabir; Turgay, Tahsin; Turkoz, Mustafa Burak; Yildirim, GurcanPresent study focuses extensively on the change in electrical, superconducting and microhardness parameters with partial substitution of trivalent V+3 impurities replacing Bi+3 ions in Bi-2212 ceramic compound with the aid of dc electrical resistivity and microhardness test measurements. Experimental findings, calculation results, and phenomenological discussions provide that the optimum vanadium substitution level is found to be x = 0.01 in the Bi2.0-xVxSr2.0Ca1.1Cu2.0Oy (Bi-2212) ceramic system for the highest conductivity, crystallinity quality, superconducting, and mechanical performance features depending on the decreased microscopic structural problems. All the findings are wholly verified by scanning electron microscopy (SEM) and X-Ray diffraction (XRD) analyses. The dc electrical measurements indicate that the optimum vanadium ions support the pairing mechanism for the formation of new polaronic states in the clusters of microdomains, and hence expand superconducting energy gap due to the enhancement of amplitude part of pair wave function in the spin-density wave systems. The excess vanadium content degrades all the basic thermodynamics and quantum mechanical quantities mentioned due to the stress-induced phase transformation. Numerically, the Bi-2212 advanced ceramic matrix prepared by the optimum vanadium impurity is noticed to present the smallest residual resistivity value of 0.08 m & omega; cm, room temperature resistivity value of 8.84 m & omega; cm, and broadening degree of 0.36 K. Similarly, the ceramic material is found to possess the highest residual resistivity ratio of 3.05, carrier concen-tration number of 0.153041, critical transition offset and onset value of 84.66 K and 85.02 K, respectively. Besides, the microhardness findings reveal that the same compound with the least sensitivity to the applied test loads exhibits the largest Hv value of 4.799 GPa, Young's moduli of 393.303 GPa, yield strength of (0.969 GPa), and elastic stiffness coefficient of 15.5574 (GPa)7/4 under the applied test load of 0.245 N. The XRD in-vestigations show that the presence of optimum vanadium impurity supports the formation of a high super-conducting phase, c-axis length, and average crystallite size. All the findings are morphologically confirmed by the SEM images. It is found that the crystallographically best crystallinity quality and view of surface morphology is observed for the optimum vanadium substitution level. All in all, new higher properties for the conductivity, crystallinity quality, surface morphology, superconducting, and microhardness parameters based on the optimum vanadium replacement encourage the Bi-2212 crystal system to use in much more application places.Öğe The effect of sintering parameters and MgO ratio on structural properties in Al7075/MgO composites: a review(Springer, 2023) Pul, Muharrem; Erdem, Umit; Turkoz, Mustafa Burak; Yildirim, GurcanIn this experimental study, Al7075 matrix composites reinforced with different proportions of MgO were produced by powder metallurgy method. Different sintering temperatures and times were applied in the powder metallurgy production process. In the second stage of the experimental study, firstly, the porosity and hardness measurements of the composite materials were made. Then, microstructure images were taken with SEM and optical microscope, and XRD analyzes were performed. Using the obtained data, the effects of different MgO ratios and different sintering parameters on the structural properties of composite materials were evaluated. As the sintering temperature increased, the density of the composite structure increased and then decreased again. Accordingly, the amount of porosity first decreased and then increased again. Significant size growth occurred in all samples sintered at 600 degrees C. This change was associated with the high amount of porosity in the same samples. A more stable microstructure was obtained from the samples sintered at 550 degrees C. Thus, it can be said that the presence of excess MgO particles in the system causes the material quality to deteriorate due to increased microscopic structural problems, wetting rates, intergranular interaction problems between adjacent layers, recovery mechanism and entanglement of voids, and dislocations. Therefore, the ideal rate, time and temperature value for MgO addition should be carefully determined. As a result, it was seen that the sintering temperature of 550 degrees C gave the most suitable results. The sintering time strengthened the phase volume of the Al7075 alloy, making the compound more stable.Öğe Evolution of dynamics of physico-chemical and mechanical properties of hydroxyapatite with fluorine addition and degradation stability of new matrices(Elsevier, 2022) Erdem, Umit; Dogan, Deniz; Bozer, Buesra Moran; Karaboga, Seda; Turkoz, Mustafa Burak; Metin, Aysegul Ulku; Yildirim, GurcanThis multidisciplinary study examined sensitively the change in the dynamics of main mechanical performance, stability of crystal structure, crystallinity quality, strength, corrosion resistance, biocompatibility, resistance to structural degradation/separations and mechanical durability features of hydroxyapatite (HAp) biomedical materials based on the fluorine addition and degradation process to guide future medical and dental treatment studies. In the study, the fluorine ions were used to be the dental coating, filling and supporting material for biologically or synthetically produced bone minerals. The general characteristic properties were investigated by means of standard spectroscopic, structural and mechanical analysis methods including RAMAN, SEM-EDS, TEM, Vickers micro-indentation hardness and density measurements. A time dependent release test was performed to evaluate possible fluorine ion release after the degradation process. It was found that the fundamental charac-teristic properties of HAp biomedical materials are noted to improve with the increase in the fluoride level up to 2% due much more stabilization of HAp crystal system. The combination of RAMAN spectra and powder XRD analyzes indicates that 2% addition level affects positively the formation velocity of characteristic HAP phase. Besides, fluorine doped HAp materials all exhibited the main characteristic peaks after degradation process. This is attributed to the fact that the fluorine ions enabled the hydroxyapatite to enhance the structural quality and stability towards the corrosion environment. However, in case of excess dopant level of 3% the degradation rates were obtained to increase due to higher contribution rate and especially electrostatic interactions. As for the surface morphology examinations, 2% fluorine added HAp with the highest density of 3.0879 g/cm3 was determined to present the superior crystallinity quality (smallest grain size, best smooth surface, honeycomb pattern, regular shaped particles and densest particle distributions through the specimen surface). Conversely, the excess fluorine triggered to increase seriously degree of micro/macro porosity in the surface morphology and microscopic structural problems in the crystal system. Thus, the HAp doped with 3% was the most affected material from the degradation process. Additionally, the fluorine ion values read after the release process were quite far from the value that could cause toxic effects. Lastly, the optimum fluorine addition provides the positive effects on the highest durability, stiffness and mechanical fracture strength properties as a consequence of dif-ferentiation in the surface residual compressive stress regions (lattice strain fields), amplification sites and active operable slip systems in the matrix. Hence, the crack propagations prefer to proceed in the transcrystalline re-gions rather than the intergranular parts. Similarly, it was found that Vickers micro-indentation hardness tests showed that the microhardness parameters increased after the degradation process. All in all, the fluorine addition level of 2% was noted to be good choice to improve the fundamental characteristic properties of hy-droxyapatite biomedical materials for heavy-duty musculoskeletal, orthopedic implant, biological and thera-peutic applications in medicine and dentistry application fields.Öğe Evolution of residual compressive stress regions in Co-diffused Bi-2212 engineering ceramics with annealing temperature(Springer, 2024) Mercan, Ali; Erdem, Umit; Ulgen, Asaf Tolga; Gulen, Mahir; Turkoz, Mustafa Burak; Turgay, Tahsin; Yildirim, GurcanThe role of diffusion annealing temperatures intervals 600-850 degrees C on durable tetragonal phase, surface morphology, and main mechanical performance parameters of Co surface-layered Bi2.1Sr2.0Ca1.1Cu2.0Oy (Bi-2212) samples has extensively been examined by scanning electron microscopy (SEM), Electron Dispersive X-ray (EDX) technique and microindentation Vickers hardness (Hv) tests. The experimental findings have shown that every material prepared has presented different composition distributions on the specimen surface as a consequence of the successful production of materials. Besides, the mechanical characteristics and durable tetragonal phase have been noted to enhance significantly with the enhancement of annealing temperature up to 650 degrees C due to the formation of new slip systems, surface residual compressive stress regions, connections between grains, and chemical bonding between the foreign and host atoms. Further, the optimum temperature has led to the reduction in stored internal strain energy and degree of granularity in the Co-diffused Bi-2212 crystal system. In this respect, the sample with the least sensitive to the external forces has exhibited the highest elastic modulus of 0.5445 GPa, shear modulus of 17.8515 GPa, yield strength of 181.5 MPa, and resilience of 369.1 MPa under 0.295 N. Accordingly, the cracks and dislocations have preferred to propagate throughout the transcrystalline regions, and crack growth size was easily controlled. Similarly, the saturation limit region has begun at relatively higher applied test load magnitudes. Conversely, the excess annealing temperature has caused the increase in the agglomeration of cobalt ions throughout the intergranular regions. Correspondingly, the activation of stress-induced phase transformation has been triggered seriously. Bi-2212 ceramic compound exposed to the optimum diffusion annealing temperature exhibits the most uniform surface view and crystalline quality with the densest surface morphology and the largest particle distributions and orientations. Moreover, every material studied has perfectly presented the characteristic indentation size effect behavior. The examination of granularity degree depending on elasticity moduli has verified all the Hv test results and discussions. All in all, this study guides the use of engineering ceramics in more application areas due to the increase in their service life.Öğe Fabrication of mechanically advanced polydopamine decorated hydroxyapatite/polyvinyl alcohol bio-composite for biomedical applications: In-vitro physicochemical and biological evaluation(Elsevier, 2022) Erdem, Umit; Dogan, Deniz; Bozer, Busra M.; Turkoz, Mustafa B.; Yildirim, Gurcan; Metin, Aysegul U.In this study, polydopamine (PDA) coated hydroxyapatite (HA) reinforced polyvinyl alcohol (PVA) films were produced to be used in biomedical applications such as bone tissue regeneration. pDA is coated not only to prevent the agglomeration of HA when encountering interstitial fluids but also to strongly bind the PVA for the interaction between materials so that the mechanical performance becomes more stabilized. pDA was coated on the hydroxyapatite surface using a radical polymerization technique, and the reinforced PVA were produced with pDA-coated HA (pDA-HA/PVA) nanoparticles. Fundamental characteristic properties of pDA-HA/PVA nanocomposite films were examined by morphological/chemical (SEM-EDS), microstructural (XRD, Ft-IR, and Raman), thermodynamic (TGA and TM), mechanical performance (Vickers microhardness) and biological activity analysis (MTT, genotoxicity and antimicrobial efficacy investigations). Physicochemical analysis showed that all the samples studied exhibited homogeneous mineral distributions through the main structures. According to TGA, TMA and hardness tests, the new composite structure possessed higher mechanical properties than neat PVA. Further, pDA-HA/PVA nanocomposites exhibited high antibacterial capacities against Acinetobacter Baumannii (A.Baumannii), Staphylococcus aureus (S. aureus), and Streptococcus mutans (S.mutans). Moreover, the new nanocomposites were noted to present good biocompatibility for fibroblast (L929) cells and to support remarkably MCS cells. All in all, this comprehensive work shows that the thermo-mechanically improved pDA-HA/PVA films will increase the application fields of PVA in biomedical fields especially tooth-bone treatments for coating, filling, or occlusion purposes.Öğe Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect(Elsevier Sci Ltd, 2020) Erdem, Umit; Dogan, Mustafa; Metin, Aysegul U.; Baglar, Serdar; Turkoz, Mustafa B.; Turk, Mustafa; Nezir, SaffetIn this study, nano sized hydroxyapatite (nHAp) and Ag(I) doped hydroxyapatite (Ag-nHAp) particles were synthesized by the precipitation method and used as a coating material for remineralization on caries-affected dentine samples. Characterization studies of both the synthesized hydroxyapatite-based particles and the coated dentine samples were performed using instrumental techniques such as SEM and FFIR, and then toxicity and antibacterial properties were also evaluated. It was observed that dentine samples were effectively coated by both nHAp and Ag center dot nHAp particles which have no toxic effects. Furthermore, the costing of nano-hydroxyapatite on dentine samples positively contributed to the viability of L929 fibroblast cells and also provided an antibacterial effect against to bacteria such as S. mutants, C. albicans and E. coli bacteria that are most frequently caused caries in the teeth. While all type of bacteria was eliminated by the nHAp coated dentine samples at 24th, Ag-nHAp coated dentine samples removed to all bacteria type at 1st.Öğe Improvement in organization of Cu-O coordination and super-electrons in Bi-2212 ceramic matrix with Ag/Sr partial substitution(Springer, 2024) Al Azzawi, Abdullah Nabel Salman; Turkoz, Mustafa Burak; Erdem, Umit; Yildirim, GurcanThis study rationalizes the reason for an increase in the electrical conductivity, crystal quality, surface morphology, and superconductive transition temperatures for Bi-2212 superconductors via scientific facts and discussions depending on replacing the optimum Ag/Sr sites in the system for the first time. Every experimental result and related calculations indicate the successful replacement of monovalent Ag+ ions for the divalent Sr2+ ions in the polycrystalline Bi-2212 structure. Moreover, it is observed that the bulk Bi-2212 ceramic prepared with a partial substitution level of x = 0.01 is observed to possess the highest electrical conductivity and superconductive transition temperatures of 84.68 K and 86.26 K for the Tcoffset\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$T_{c}<^>{offset}$$\end{document} and Tconset\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$T_{c}<^>{onset}$$\end{document}, respectively. Besides, in the case of the optimum replacement level, the Bi-2212 ceramic exhibits the most uniform and smoothest surface appearance, highest interactions between the grains, best microcrystal distributions/orientations, and largest average crystalline distribution along the crystal structure. In this regard, this study becomes a leader in broadening the application spectra including the heavy-industrial technologies, innovative, advanced engineering-related sectors, and large-scale application fields for Bi-2212 superconducting ceramics.Öğe La3+ and F- dual-doped multifunctional hydroxyapatite nanoparticles: Synthesis and characterization(Wiley, 2021) Erdem, Umit; Turkoz, Mustafa B.Hydroxyapatite (HA) co-doped with La3+ and F- ions were synthesized by the precipitation method and sintered at 1,100 degrees C for 1 hr. Samples were characterized by the standard experimental methods including the density, X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy (SEM) to investigate their microstructure, phase formation, and bonding characteristics in detail. Moreover, the materials produced were identified using the microhardness tests. It was observed that in the most of materials, the hydroxyapatite was found to be the main phase with a minor amount of beta-tricalcium phosphate (beta-TCP). Furthermore, the presence of fluoride and small amount of beta-TCP was verified with all the characteristic FTIR bands of hydroxyapatite for the majority of samples studied. The result in SEM evaluation is that the produced HA powders have less deformed, uniformly distributed, and regularly shaped particles. Here, the material density has changed towards a less dense state with the increasing rate of La doping, but statistically significant difference was not obtained (p, .1942 > .05) with increase of the F doping. A significant difference was obtained the microhardness values between La3+ and F- ions co-doped HA materials and pure HA (p [.0053] < .05). Accordingly, this study confirmed that since the La3+ and F- ions can potentially increase the efficacy of HA. According to the spectral, mechanical, and microstructure analysis result, this material can be as a good candidate product for use as an occluding material for dental application.Öğe Refinement of fundamental characteristic properties with homovalent Er/Y partial replacement of YBa2Cu3O7-y ceramic matrix(Elsevier Science Sa, 2021) Erdem, Umit; Turkoz, Mustafa B.; Yildirim, Gurcan; Zalaoglu, Yusuf; Nezir, SaffetIn the current work, the effect of partial substitution of Er-sites for the Y-sites in the bulk YBa2Cu3O7-y (YBCO) crystal system on the fundamental superconducting, electrical, crystallinity and structural morphology features is examined together with the reasons by means of powder X-ray diffraction (XRD), temperature-dependent electrical resistivity (rho-T), scanning electron microscopy (SEM), electron dispersive X-ray (EDX) investigations and deduced calculation parameters. All the experimental test results show that the erbium impurities are suc-cessfully substituted by the yttrium sites in the bulk Y-123 crystal system, confirmed by sensitively the EDX and rho-T measurement results. Moreover, it is found that all the fundamental characteristic quantities improve with the increment in the Er/Y partial substitution level up to the value of x = 0.03 beyond which the features tend to degrade dramatically. In this respect, the bulk Y1-xErxBa2Cu3O7-y ceramic compound prepared within the molar ratio of x = 0.03 crystallizes in the orthorhombic space group P-4/ mmm with a little distortion due to the refinement in the crystallinity quality, crystallite growth, oxygen ordering degree, scattering mechanism, intra and intergrain boundary couplings, grain alignment distributions and orientations. The XRD results show that the optimum erbium content enables to develop seriously the fundamental crystallographic features (lattice strain, lattice cell constants, crystallite size distribution, dislocation density ratio, oxygen concentrations in the unit cells) of Y-123 crystal structure. However, the excess Er/Y substitution leads to enhance considerably the systematic structural problems and inhomogeneous distribution of strains (formed by the structural defects) in the YBCO crystal structure. Thus, the phase transition from orthorhombic to tetragonal (structural O-T transition) crystal structure is observed. In fact, the XRD result displays that the trivalent Er3+ particles may partially be replaced by the divalent Cu2+ host atoms in the bulk Y-123 crystal structure after the critic substitution level of x = 0.03. The optimum Er concentration causes to form more thermodynamically activated super-electrons in the homogeneous superconducting cluster percentages in the paths due to the induced polaronic effect, and accordingly the intrinsic overdoped nature of Y-123 ceramic system transits into optimally doped state. Similarly, the erbium ions enable to increase the mobile hole carrier concentration and homogeneities in the oxidation state of superconducting grains. Namely, the amplitude of pair wave function (Psi=Psi(0)e(-i phi)) is strength enough to form bipolarons in the polarizable lattices and localize of densities of electronic states (DOS) at Fermi level. SEM investigations picture that the surface morphology view and crystallinity quality develop remarkably with the increment in the erbium content up to the critical dopant level of x = 0.03 where the sample exhibits the best grain alignment orientations, densest and smoothest surface morphology with the combination of lowest porous and largest particle distributions well linked each other. All in all, this comprehensive work based on the analysis of Er/Y partial replacement mechanism along the YBa2Cu3O7- y ceramic matrix may open up a newly/novel and feasible area for the advanced engineering, heavy-industrial technology and large-scale applications of type-II superconducting materials. (C) 2021 Elsevier B.V. All rights reserved.Öğe Resorbable membrane design: In vitro characterization of silver doped-hydroxyapatite-reinforced XG/PEI semi-IPN composite(Elsevier, 2023) Dogan, Deniz; Erdem, Umit; Bozer, Busra M.; Turkoz, Mustafa B.; Yildirim, Gurcan; Metin, Aysegul U.In this study, the production and characterization of silver-doped hydroxyapatite (AgHA) reinforced Xanthan gum (XG) and Polyethyleneimine (PEI) reinforced semi-interpenetrating polymer network (IPN) biocomposite, known to be used as bone cover material for therapeutic purposes in bone tissue, were performed. XG/PEI IPN films containing 2AgHA nanoparticles were produced by simultaneous condensation and ionic gelation. Characteristics of 2AgHA-XG/PEI nanocomposite film were evaluated by structural, morphological (SEM, XRD, FT-IR, TGA, TM, and Raman) and biological activity analysis (degradation, MTT, genotoxicity, and antimicrobial activity) techniques. In the physicochemical characterization, it was determined that 2AgHA nanoparticles were homogeneously dispersed in the XG/PEI-IPN membrane at high concentration and the thermal and mechanical stability of the formed film were high. The nanocomposites showed high antibacterial activity against Acinetobacter Baumannii (A.Baumannii), Staphylococcus aureus (S.aureus), and Streptococcus mutans (S.mutans). L929 exhibited good biocompatibility for fibroblast cells and was determined to support the formation of MCC cells. It was shown that a resorbable 2AgHA-XG/PEI composite material was obtained with a high degradation rate and 64% loss of mass at the end of the 7th day. Physico-chemically developed biocompatible and biodegradable XG-2AgHA/PEI nanocomposite semi-IPN films possessed an important potential for the treatment of defects in bone tissue as an easily applicable bone cover. Besides, it was noted that 2AgHA-XG/PEI biocomposite could increase cell viability, especially in dental-bone treatments for coating, filling, and occlusion.Öğe Silver release of Ag (I) doped hydroxyapatite: In vitro study(Wiley, 2019) Erdem, Umit; Turkoz, Mustafa B.A material is produced by doping of silver (Ag (I)) which has antibacterial property to nano hydroxyapatite (nHAp), to remove the hipersensitivity in the teeth by closing the dentine tubules or dental micro cracks of the teeth and effective against for some bacteria. The doping of Ag (I) can also produces a toxic effect. Ag (I) can be released from the structure as a result of biological, physical and chemical effects and may cause toxicity. Therefore, it is important to determine whether the presence of Ag (I) has a toxic effect. In this study, Ag (I)-doped nHAp was synthesized by precipitation method and tried to determine the release values as a function of time compared to the doping rate by using the ICP-OES. Also, the products we produce in simulated body fluid were kept for retention periods of 4-20 weeks to determine degradation percentages. A cytotoxicity study was performed to observe the toxic effect that may be caused by possible Ag (I) release. According to the analysis, the release values in all products were observed in ppb level. And it is concluded that the materials produced are not degraded. Cell viability values of more than 70% were obtained. It was observed that the release of Ag (I) bound to Ag (I)-doped nHAp hexagonal structure was very low. It was concluded that the products are not degraded and Ag (I)-doped nHAp to a certain ratio is a biocompatible material that can be used in dentistry for treatment.Öğe Spectral analysis and biological activity assessment of silver doped hydroxyapatite(Taylor & Francis Ltd, 2021) Erdem, Umit; Bozer, Busra Moran; Turkoz, Mustafa B.; Metin, Aysegul U.; Yildirim, Gurcan; Turk, Mustafa; Nezir, SaffetIn this study, the hydroxyapatite biomaterials are produced by the precipitation method and the role of silver doping within the different molar ratios of 2.0, 5.0, and 10.0% are investigated with some fundamental analysis, including powder XRD, SEM, EDS, FTIR, Raman, and material densities. In vitro biocompatibility assessment is conducted with cytotoxicity and agar diffusion tests. Moreover, genotoxicity tests determine whether the biomaterials produced cause the mutations or not. In addition, a hemolytic effect test examines the variation of hemolytic behavior of compounds. Also, the cell migration experiments inspect the influence of silver ion levels in biomaterials on many biological processes. The experimental results reveal that the honeycomb-patterned morphological structures are obtained for all the products. FTIR and Raman analyses reveal that the dramatic changes in the characteristic functional group peaks are obtained with the increment in the amount of silver ions. The experimental parts related to the biocompatibility assessment of the study show that there seems to be deterioration in biocompatibility as the silver ion-doping level increases in the system. To sum up, the ideal doping value for bone tissue engineering applications is found to be 2%.Öğe Variation of fundamental features of cobalt surface-layered Bi-2212 superconductor materials with diffusion annealing temperature(Elsevier Sci Ltd, 2023) Oz, Ilker; Terzioglu, Cabir; Oz, Muhammed; Ulgen, Asaf Tolga; Turkoz, Mustafa Burak; Erdem, Umit; Yildirim, GurcanThe present study appears extensively on the role of diffusion annealing temperature intervals 650-850 degrees C on electrical conductivity, flux pinning ability, superconducting and crystallinity quality of Cobalt (Co) surface -layered Bi-2212 compounds with experimental tests including dc resistivity, bulk density, X-ray diffraction, critical current density measurements, and theoretical calculations. Experimental findings display that the Co ions may be replaced mostly by bismuth sites in the crystal lattice as a consequence of appropriate cation -vacancy, electron configurations of the outer shell, chemical valence states, and electronegativity of chemical contents in the main composition. The fundamental characteristic features refine considerably with 650 degrees C annealing temperature due to enhancement of antiferromagnetic spin fluctuations in the clusters of micro -domains, re-ordering of Cu-O bonds, stabilization of system, pairing mechanism, modulation of insulating Bi-O double layers, and orbital hybridization mechanisms. Accordingly, bulk Bi-2212 ceramic obtained at optimum annealing temperature exhibits the best conductivity because of a decrease in systematic crystallinity problems and potential grain boundary interaction problems expected in the system. Likewise, the optimum annealing temperature triggers the artificial nucleation regions for 2D discrete pancakelike Abrikosov vortices to decelerate thermal fluxon movements. Moreover, the X-ray diffraction results indicate that optimum Co ions in crystal lattice significantly improve crystal structure quality, grain alignment distributions in c-axis orientation, the extension of high-Tc Bi-2223 superconducting phase, and average crystallite size parameters. Additionally, the nucleation activation energy is noticed to reduce with optimum Co ions due to enhancement in the nucleation stability and crystallization temperature values to higher temperature zones. Namely, optimum Co ions easily diffusing into the lattice points support the formation of surface nucleation. In contrast, after a critical value of 650 degrees C, the characteristic properties mentioned suppress remarkably. In conclusion, the main characteristic features are extensively improved by the optimum diffusion annealing temperature for usage in novel and feasible market areas.
