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Öğe ATYPICAL RECURRENCE PRESENTATION OF PRE-TRANSPLANT PERIOD MULTIPLE MYELOMA: MULTIPLE INTRACRANIAL PLASMACYTOMAS WITH INTRATUMORAL HEMORRHAGE(Pergamon-Elsevier Science Ltd, 2016) Yildiz, A.; Inci, F.; Koroglu, M.[No abstract available]Öğe COMPLEMENTARY AND ALTERNATIVE MEDICINE AWARENESS IN CANCER PATIENTS RECEIVING CHEMOTHERAPY(Verduci International, 2020) Inci, H.; Inci, F.Objective: We aimed at investigating the knowledge and attitudes of cancer patients who underwent chemotherapy about Complementary and Alternative Medicine (CAM). Patients and Methods: 306 cancer patients filled the CAM questionnaire. The patients were evaluated in terms of frequency of CAM use and CAM type, source of information, and reason for use and some other factors. Results: 92.8% of the patients had knowledge about CAM. 63.4% of them used one of the CAM methods. The patients generally used the CAM method thinking it may provide additional benefit to cancer treatments. Conclusions: It was observed that the rate of CAM use among the cancer patients were high. The patients obtained the information about CAM mostly through the media. Education level, disease stage, and place of residence were the independent predictive factors for the CAM use. They tended to use phytotherapy more often than other applications due to the fact that it has been used in our country for years. © 2020, Verduci International. All rights reserved.Öğe COMPLEMENTARY AND ALTERNATIVE MEDICINE AWARENESS IN CANCER PATIENTS RECEIVING CHEMOTHERAPY(Verduci Publisher, 2020) Inci, H.; Inci, F.Objective: We aimed at investigating the knowledge and attitudes of cancer patients who underwent chemotherapy about Complementary and Alternative Medicine (CAM). Patients and Methods: 306 cancer patients filled the CAM questionnaire. The patients were evaluated in terms of frequency of CAM use and CAM type, source of information, and reason for use and some other factors. Results: 92.8% of the patients had knowledge about CAM. 63.4% of them used one of the CAM methods. The patients generally used the CAM method thinking it may provide additional benefit to cancer treatments. Conclusions: It was observed that the rate of CAM use among the cancer patients were high. The patients obtained the information about CAM mostly through the media. Education level, disease stage, and place of residence were the independent predictive factors for the CAM use. They tended to use phytotherapy more often than other applications due to the fact that it has been used in our country for years.Öğe Depression, anxiety and coping strategies in cancer patients: A case control study(Ankara Yildirim Beyazit University, 2019) Ersoy, S.; Inci, H.; Inci, F.; Engin, V.S.; Adahan, D.Objectives: Psychiatric disorders frequently accompany chronic diseases especially cancer. The aim of this study was to investigate the depression and anxiety levels and the coping strategies in cancer patients. Materials and Methods: This was a case control study conducted in Karabuk University Research Hospital (KURH) between January 2018 and December 2018. Case group constituted of patients with an established diagnosis of cancer and control group included healthy individuals. Coping Strategies Questionnaire (COPE), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were performed for all participants. Statistical analyzes were carried out using Minitab 17 Statistical Software. Case versus control comparison for continues variables was conducted using Mann Whitney U test. Degree of relationship between continues variables were measured using Spearman's rank correlation. Chi-Squared test was used to evaluate cross tabulated categorical data. Results: 94 individuals were included in the study. Both cancer and control groups consisted of 23 males and 24 females. Mean age was found 59.77±12.01 years for cancer patients and 59.06±12.36 for control group. BDI and BAI scores of the patients were significantly higher compared to healthy individuals. Considering the cut-off values; 60% (28/47) of the cancer patients were found depressed and 62% (29/47) of them were found to have anxiety while in the control group both the depression and anxiety prevalence was 28% (13/47) (p=0.004 and p=0.002 respectively). Both groups were similar regarding the coping strategies total score (p=0.779). Turning to religion, humor, mental disengagement, denial and substance use were seen more frequently in cancer patients compared to control group (p=0.004, p=0.001, p=0.005, p=0.001 and p=0.004 respectively); whereas active coping, restraint coping, acceptance and behavioral disengagement were significantly more frequent in control group (p=0.001, p=0.039, p=0.026 and p=0.055 respectively). Humor, mental disengagement, denial and substance use were positively correlated with BDI scores (r=0.30 p=0.003, r=0.38 p=0.001, r=0.29 p=0.004, r=0.22 p=0.03 respectively). Turning to religion, humor, mental disengagement and substance use were positively correlated with BAI scores (r=0.24 p=0.015, r=0.25 p=0.013, r=0.31 p=0.001, r=0.23 p=0.024 respectively). Conclusion: The results of the current study revealed that cancer patients had higher levels of depression and anxiety compared to healthy individuals and they had higher risk of being depressed or anxious. Furthermore, the patients developed different strategies in order to cope with the burden of this catastrophic disease. Therefore, cancer is a multifaceted condition which must be approached in a multidimensional manner, by taking psychological features of each individual into account. © 2019 Ankara Yildirim Beyazit University. All rights reserved.Öğe The effects of smoking cessation on the ratios of neutrophil/lymphocyte, platelet/lymphocyte, mean platelet volume/lymphocyte and monocyte/high-density lipoprotein cholesterol(2023) Inci, H.; Besler, M.S.; Inci, F.; Adahan, D.The amount of smoking, level of smoking addiction and smoking cessation have effects on blood cells, blood lipid levels, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), mean platelet volume (MPV)/lymphocyte ratio (MPVLR) and monocyte/high- density lipoprotein (HDL) ratio (MHR). Methods In this self-controlled experimental study, we included individuals who applied to a smoking cessation clinic and quit smoking. Their sociodemographic and clinical characteristics, the amount of cigarettes consumed (pack/year), their Fagerstrom test for nicotine dependence (FTND) results, haemogram values before and 6 months after quitting smoking, NLR, PLR, MPVLR, MHR and blood lipid levels before and after the treatment were compared retrospectively. Results The mean (SD) age of the 239 individuals who participated in the study was 41.7 (10.9) years and 55.2% of them were women. Their mean FTND score was 7.06 (2.0), and most of them (47.7%) had a very high level of addiction. After the smoking cessation treatment, their neutrophil, platelet, MPV, red cell distribution width, platelet distribution width (PDW), cholesterol, triglyceride, low- density lipoprotein, NLR, PLR, MPVLR, MHR and HDL values increased (p<0.05). The amount of smoking and level of dependence were negatively correlated with HDL, and positively correlated with other parameters. Conclusion After smoking cessation, in addition to dyslipidaemia, the NLR, PLR, MPVLR and MHR values also decreased, and the difference was found to correlate with the level of addiction and the amount of smoking.Öğe IS LOW SERUM VITAMIN D LEVEL ASSOCIATED WITH CANCER?(Verduci Publisher, 2020) Inci, F.; Inci, H.; Karatas, F.; Adahan, D.Objective: The aim of this study is to determine the importance of serum Vitamin D (VD) levels in cancer pathogenesis and to investigate its relationship with cancer subtypes. Patients and Methods: This study included 4914 individuals, 1027 cancer patients and 3887 healthy subjects. The cancer patients were divided into five groups by cancer subtypes. The cancer patients and those in the control group were compared in terms of serum VD levels. Results: In the patients with cancer, the mean serum VD level was found to be significantly lower than that in the control group (16.1 +/- 10.6 ng/mL vs. 19.6 +/- 10.4 ng/mL, p = 0.000). The VD levels were higher in breast cancer (BC) group than those in other cancer groups. The mean serum VD level was significantly lower in the BC group compared to the control group (18.1 +/- 11.3 ng/mL vs. 19.6 +/- 10.4 ng/mL, p = 0.004). In the ROC analysis, the cut-off VD value was determined as 15.2 ng/mL between those with and without cancer (area 0.634, OR: 95% CI 0.612-0.656, p = 0.000). VD <15.2 ng/mL was independently associated with cancer (OR, 2.096; 95% CI: 1.595 - 2.756, p = 0.000). Moreover, the decreased VD level was found to be independently associated with the increased cancer risk (OR, 1.048; 95% CI: 1.032- 1.065, p = 0.000). Conclusions: Although there was no difference in VD levels among the cancer patients and there was less difference in the BC patients compared to the healthy individuals, the VD level was significantly lower in all cancer patients compared to healthy people. In addition, there was an independent positive association between VD levels and cancer, with the VD values below 15.2 ng/mL increasing the cancer risk.Öğe Paclitaxel-induced hepatic steatosis in patients with breast cancer(Zerbinis Publications, 2019) Inci, F.; Karatas, F.Purpose: Paclitaxel has been associated with serum aminotransferase elevations, however, paclitaxel induced hepatosteatosis has not been evaluated systematically. This study assessed the rate of paclitaxel-related hepatosteatosis. Methods: Forty one early breast cancer (BC) patients were included the study. Hepatic ultrasonograpy, demographic features and biochemical liver function tests before and after 12 weeks of paclitaxel were assessed. Results: New-onset hepatosteatosis was developed in 26.7% of the patients. Baseline triglyceride>200mg/dL (OR, 11.25; p=0.015), LDH at baseline >191.48 IU/L (OR, 4.93; p=0.048), and total bilirubin >0.51 mg/dL after paclitaxel (OR, 6.17; p=0.042) were found as independent prognostic markers for new-onset hepatosteatosis. Conclusion: Paclitaxel may induce hepatosteatosis in patients with BC. © 2019 Zerbinis Publications. All rights reserved.Öğe Pain catastrophizing, depression, and anxiety in fibromyalgia patients(Ondokuz Mayis Universitesi, 2023) Inci, H.; Inci, F.Psychiatric findings may be seen in Fibromyalgia (FM) patients. We aimed to evaluate the relationship between anxiety, depression, and pain catastrophizing in FM patients and normal individuals. The study group consisted of FM patients and a healthy control group. Socio-demographic data form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Visual Analogue Scale (VAS), Fibromyalgia Impact Questionnaire (FIQ), and Pain Catastrophizing Scale (PCS) were administered to the participants. It was evaluated whether there was a statistical difference between the groups in terms of BDI, BAI, PCS, VAS, and FIQ. Of the 178 patients in our study, 85 were FM patients and 93 were control groups. The BDI, BAI, PCS, PCSH (PCS Helplessness), PCSM (PCS Magnification), and PCSR (PCS Rumination) were found to be higher in FM patients compared to the control group. The FM patients were found to have moderate depression according to the BDI score (18.7±10.6) and moderate anxiety according to the BAI score (16.5±9.9). There was a positive correlation between BDI and BAI, FIQ and VAS, PCS and BDI, BAI and FIQ, and BAI and FIQ. It was found that the FM patients had “moderate” depression and anxiety, and their level of pain catastrophizing increased with the increase in depression and anxiety severity. © 2023 Ondokuz Mayis Universitesi. All rights reserved.
