Yazar "Koroglu, Mustafa" seçeneğine göre listele

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    Assessing Safety of Pneumatic Tube System (PTS) for Patients with Very Low Hematologic Parameters
    (Int Scientific Information, Inc, 2016) Koroglu, Mustafa; Erkurt, Mehmet Ali; Kuku, Irfan; Kaya, Emin; Berber, Ilhami; Nizam, Ilknur; Yagar, Yavuz
    Background: Preventive interventions save lives during the process of chemotherapy for hematologic malignancies, when a hematology laboratory can ensure accurate results. The use of a pneumatic tube system (PTS) is associated with measurement errors and unnecessary transfusions. The aim of this study was to evaluate pre-analytical errors associated with transportation method (PTS versus hand-delivered) and to investigate whether there are unnecessary transfusion events in pancytopenia leukemia patients with very low hematological parameters. Material/Methods: A total of 140 paired blood collections were performed for hemogram and biochemistry assays. Paired EDTA and serum gel blood samples were collected from 58 cases with acute leukemia on different days. For each pair, one sample was hand-delivered by a courier (Group 1) while the other sample was transported through a PTS (Group 2). Results: The hand-delivered method showed that some platelet transfusions were unnecessary for different thrombocyte cut-off values. Calculated unnecessary platelet (PLT) transfusion ratios when using PTS (PLT <30x10(3)/mu L, 16.3%; PLT <25x10(3)/mu L, 16.4%; PLT <20x10(3)/mu L, 80.3%; PLT <15x10(3)/mu L, 48.6%; and PLT <10x10(3)/mu L, 150.0%) were found to be statistically significant (p=0.002, p=0.046, p<0.000, p=0.028, and p<0.000, respectively). In contrast, for RBC transfusion ratios, although the ratios were high in Group 2, we found no significant difference between the two groups; (HGB <8.0 g/dL, 23.3%; HGB <9.0 g/dL, 25.0%, HGB<10.0 g/dL, 19.3%) and (p=0.002, p=0.085, p<0.160, and p=0.235, respectively). Conclusions: Although our results cannot be universally applied, physicians should be careful, skeptical, and suspicious of transfusion decisions in hematology clinics and consider potential analytical and pre-analytical errors in cases of severe cytopenia when using PTS.
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    The effect of ferritin, vitamin B12 and folic acid on pregnancy outcomes
    (E-Century Publishing Corp, 2016) Kalem, Pinar; Benli, Ali Ramazan; Koroglu, Mustafa; Benli, Neriman Cetin; Koyuncu, Murat; Cesur, Ozkan; Dane, Pakizer Banu Kilicoglu
    Purpose: A reduction occurs in levels of some minerals and vitamins due to physiological adaptation during pregnancy, and this situation causes anemia in pregnancy. The aim of the present study was to evaluate the effect of ferritin, vitamin B12 and folate levels on outcomes of pregnancy in 3rd trimester pregnant women. Materials and Methods: This retrospective study included a total of 72 pregnant women in the third trimester of pregnancy. Vitamin and mineral analyses of the patients were applied. Patients were questioned in respect of whether or not iron and vitamin supplements were taken during pregnancy, the mode of delivery and the history of postpartum problems in infant. Results: As the number of children increased, so an increase was seen in the incidence of anemia. Of the mothers of newborns with medical problems, 60% had anemia. There was no statistically significant difference in the mean birth weight according to the presence or absence of maternal anemia. Anemia in pregnant women is defined as hemoglobin level below 11.0 g/dL in the first and third trimester and below 10.5 g/dL in the second trimester. No significant difference was determined in anemia status according to the mode of delivery. No difference in anemia was detected in infants, regardless of whether or not their mothers took vitamin and mineral supplements. Conclusion: Anemia in the third trimester has no effect on the mode or time of delivery, weight and general condition of the newborn. To decide the effect of anemia on the outcome of pregnancy, further studies with more participants are needed.
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    Moxifloxacin related thrombocytopeniae: A case report
    (Turkish Assoc Tuberculosis & Thorax, 2016) Cortuk, Mustafa; Benli, Ali Ramazan; Koroglu, Mustafa; Yazici, Onur; Acat, Murat; Casim, Hasan; Cetinkaya, Erdogan
    Drug-induced thrombocytopenia can be caused by various medications, most frequently, antibiotics. There have been reports of thrombocytopenia cases due to the usage of quinolone antibiotics, although moxifloxacin-related thrombocytopenia has been reported very rarely. The case is here presented of a 60-year old male with chronic obstructive pulmonary disease who presented with complaints of progressively worsening dyspnea. After hospitalization, progressive thrombocytopenia was detected which had started on the 3rd day of moxifloxacin treatment. Other causes of thrombocytopenia were excluded and the thrombocyte count returned to normal after discontinuation of moxifloxacin.