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    Asthma control, coronaphobia and physical activity levels of children with asthma in social isolation during the COVID-19 pandemic Pysical activity of children with asthma during pandemic
    (Mediton Publishing House, 2023) Onal, S.N.; Mermerkaya, G.; Kutukcu, E.C.; Saglam, M.; Mermerkaya, H.H.
    Objective: We aimed to evaluate children and adolescents with asthma in terms of asthma control, social isolation, coronaphobia, and physical activity (PA) level during the pandemic. Methods: In this cross-sectional, prospective study, 45 patients with childhood asthma and 49 healthy peers aged 6-18 years were included. The Asthma Control Test (Child: C-ACT/Adolescent: ACT), Physical Activity Questionnaire (Child: PAQ-C/Adolescent: PAQ-A), and the social isolation (days/month) and coronaphobia questions created by the researchers were applied via the Google Forms link address. Results: ACT scores were found to be 22.1±0.7 for C-ACT and 22.2±0.6 for ACT. The mean PAQ-C scores were 2.4±0.8, 2.6±0.7 in asthmatic and healthy children respectively, the mean PAQ-A scores were 2.1±0.6, 2.4±0.7 in asthmatic and healthy adolescents respectively. Whereas 15 (71.4%) of children with asthma were inactive, 19 (79.2%) of adolescents with asthma were inactive during the pandemic. Fear of hospitalization due to COVID-19 infection was higher in the asthmatic adolescent group than healthy peers (p<0.001). The families of adolescents with asthma went outside the home to open and closed areas for more days during the pandemic (p=0.004 for outdoors, p<0.001 for indoors). Conclusions: During COVID-19, adolescents with asthma had a greater fear of hospitalization, and their families adhered less to social isolation and stay-at-home precautions. PA was similarly low in both asthmatic and healthy children/adolescents. The interventions for the negatively affected PA both in asthmatic and healthy children/adolescents and concerns related to COVID-19 infection should be considered by health professionals during and after the pandemic. © 2023, Mediton Publishing House. All rights reserved.
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    Nonsurgical periodontal therapy with/without diode laser modulates metabolic control of type 2 diabetics with periodontitis: a randomized clinical trial
    (Springer London, 2016) Koçak, E.; Saglam, M.; Kayis, S.A.; Dündar, N.; Kebapçilar, L.; G.Loos, B.; Hakki, S.S.
    In order to evaluate whether nonsurgical periodontal treatment with/without diode laser (DL) decontamination improves clinical parameters, the levels of IL-1?, IL-6, IL-8, intercellular adhesion molecule (ICAM), and vascular cell adhesion molecule (VCAM) in gingival crevicular fluid and metabolic control (HbA1c) in chronic periodontitis (CP) patients with diabetes mellitus type 2 (DM2). Sixty patients with DM2 and CP were randomly assigned into two groups to receive scaling and root planing (SRP, n = 30) or SRP followed by diode laser application (SRP + DL, n = 30). Clinical periodontal and gingival crevicular fluid (GCF) parameters were assessed at baseline, 1, and 3 months after periodontal treatment. HbA1c levels were evaluated at baseline and 3 months post-therapy. Total amounts of cytokines and molecules were analyzed by ELISA. Nonsurgical periodontal treatment with/without DL appeared to improve clinical, biochemical parameters, and glycemic control in DM2 patients (BMI < 25 kg/m2) with CP. The SRP + DL group provided better reductions in probing depth (PD) and clinical attachment level (CAL) parameters compared to the SRP group (P < 0.05). Significant reductions were found in the total amounts of GCF levels of IL-1, IL-6, IL-8, ICAM, and VCAM after treatment (P < 0.05). HbA1c levels decreased significantly at 3 months after treatment (P < 0.05). SRP + DL reduced HbA1c levels more significantly compared to SRP alone (0.41 vs. 0.22 %, P < 0.05). SRP, especially in combination with DL, shows improvement of glycemic control for DM2 patients with CP. © 2016, Springer-Verlag London.