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Öğe Anxiety in mothers of infants newly diagnosed with cow's milk protein allergy: A cross-sectional study(Mattioli 1885, 2021) Sevinc, Nergiz; Korkut, Burcu; Sevinc, EylemIntroduction and Objectives: Anxiety symptoms are common in mothers of food-allergic children. Although cow's milk protein allergy (CMPA) is the most common food allergy in infants, little is known about whether CMPA has a known effect on anxiety in mothers. The first aim was to assess the anxiety levels in mothers of infants newly diagnosed with CMPA and compare to controls. The second aim was to determine whether there is a difference in anxiety levels of mothers by the symptoms of infants with CMPA. Materials and methods: Mothers of seventy-three infants newly diagnosed with CMPA and 78 mothers of healthy infants were enrolled in this study. The CMPA group were divided into 5 subgroups according to symptoms of infants. The anxiety scores of the mothers were measured with State-Trait Anxiety Inventory (STAI). Results: The median score of the STAI-State (46 vs. 24) and the median score of the STAI-Trait (47 vs. 24) were significantly higher in CMPA group than the control group (p<0.001). The scores of both STAI-State and Trait significantly different between mothers of infants presented hematochezia and respiratory symptoms-anaphylaxis (p=0.002 for STAI-State vs p=0.008 for STAI Trait). Additionally, there was a statistically significant difference between the educational levels of mothers in CMPA group and STAI State-Trait anxiety median scores (p<0.013, p<0.001 respectively). Conclusion: This study revealed mothers of infants newly diagnosed with CMPA had high anxiety levels. In addition, it was observed having infants suffering from anaphylaxis or hemotochesia and low educational status increased the anxiety in mothers.Öğe Assessment of Knowledge, Attitudes, and Behaviors of Turkish Women on Breast and Cervical Cancer in Karabuk Province, Turkey(Univ Indonesia, 2020) Sevinc, Nergiz; Oral, Belgin; Korkut, BurcuBreast and cervical cancer incidence and mortality among women have been increasing worldwide. This cross-sectional study aimed to evaluate women's knowledge, attitudes, and behaviors regarding breast and cervical cancers. The sample was composed of 507 women aged 18 years and older who were admitted to a primary health care center in Karabuk, Turkey, from October to December 2019. The data was obtained using a questionnaire consisting of 34 questions regarding participants' socio-demographic characteristics, knowledge, attitudes, and behaviors toward breast and cervical cancers. The mean age of the participants was 41.3 +/- 12.0 years and 68.4% of them were married. Slightly more than seven in ten participants knew that the most common cancer in women was breast cancer. Almost six in ten knew that breast self-examination was the first method in the early diagnosis of breast cancer. Breast self-examination practice was found to be significant among university graduates. Periodic mammography and pap smear screenings among participants were 21.9% and 23.3%, respectively. Only 3.4% of participants had received the HPV vaccine and there was no significant difference between socio-demographic characteristics and HPV vaccination status (p-value > 0.05). Participants had moderate knowledge about breast and cervical cancer. Access to cancer screening programs should be facilitated and increased, considering these cancers' public health importance.Öğe Blood and faecal lead levels in children with various functional gastrointestinal disorders(Ediciones Doyma S A, 2020) Sevinc, Nergiz; Bilici, Namik; Sevinc, Eylem; Dogan, ErkanIntroduction: To investigate the blood lead levels (BLLs) and faecal lead levels (FLLs) in children with various functional gastrointestinal disorders (FGIDs) and compare them with controls. Patients and methods: One hundred and 2 children with FGIDs defined by the Rome IV criteria, aged 4-18 years, and one hundred and 2 sex matched healthy children were enrolled in the study. Children with FGIDs were divided into 3 subgroups as functional constipation (FC) (n = 36), functional abdominal pain (FAP) (n = 36) and functional nausea (FN) (n = 30). The lead levels were measured using atomic absorption spectrometer. Results: The median BLLs in the FGIDs group was significantly higher than in controls (5.12 and 1.77 mu g/dL, respectively). The BLLs were above 5 mu g/dL in 51,9% of children with FGIDs. There was statistically significant difference in BLLs between FC subgroup and the other subgroups (FAP and FN) (P=.003, P<.001 respectively). The FLLs in the FGIDs group was significantly higher than in controls (28.08 and 0.01 mu g/g, respectively). There was no significant difference in FLLs between FC subgroup and the other subgroups (P=.992, P=.989 respectively). No significant relation found between BLLs and FLLs of the FGIDs group (P =.123). Conclusion: This study revealed that children with FGIDs had higher BLLs and FLLs than controls and also more than half of children with FGIDs had BLLs >= 5 mu g/dL which is toxic level. These results might revive the question of whether or not clinician need to evaluate routine BLLs in children with FGIDs. (C) 2020 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U.Öğe Blood and Stool Arsenic Levels Are Decisive for Diagnosing Children's Functional Gastrointestinal Disease (FGD)(Springernature, 2022) Bilici, Namik; Dogan, Erkan; Sevinc, Eylem; Sevinc, Nergiz; Akinci, Gulsema; Musmul, Ahmet; Cengiz, MustafaPediatric gastroenteritis is a potentially fatal disease that accounts for 10% of childhood deaths. The main risk is environmental factors and nutrition. Arsenic (As) is commonly found in the earth's crust. As is an essential element that can form many organic compounds. In children, it causes diarrhea, gums, tongue lesions, diabetes, conjunctivitis, ocular opacity, and impaired immune response. It also causes low growth, mental retardation, and neurological problems. It is also known as the cause of many cancers that originate at an early age. Regionally, there is an iron and steel industry for almost a century. According to the Rome IV criteria, the blood and stools of 50 children aged 6-18 years, male and female, living in our province with functional gastrointestinal disease (FGD), were screened for As, and compared with the Healthy group (control) of 30 children. The results were evaluated with the Mann-Whitney Rank Sum Test. When blood and stool As values in males were compared with control samples, a high level of significance (p = 0.001) was found between both blood and stool As values in sick males and the control group (p < 0.005). In females, blood and stool As median values were also highly significant when compared with the control group (p = 0.001). According to these data, when the sick children (children with male and female gender) are compared with the healthy ones, the difference is highly significant (p < 0.005). High blood As levels in children indicate environmental pollution. It can be said that blood As levels are high as a result of food, water, and inhaler exposure. The presence of a high level of significant difference in stool means that the amount of As is high in the foods consumed daily. High levels of As are in blood and stools; It was evaluated that FGD could be the cause of nausea, diarrhea, vomiting, and colic. The increase in blood and stool As values due to environmental pollution is an important reason for FGD. For diseases of uncertain cause (such as FGD) resulting from chronic As exposure, blood and especially stool As values are more significant than urinary As levels. In conclusion, As a diagnostic criterion, it was concluded that blood and stool As values are an important marker in children with functional abdominal pain with other metals.Öğe Effects of chronic diseases and polypharmacy on death anxiety Polypharmacy on death anxiety(Bayrakol Medical Publisher, 2021) Korkut, Burcu; Sevinc, NergizAim: Chronic diseases and polypharmacy are medical conditions that have negative effects on quality of life and mental state. The aim of this study is to investigate the effects of chronic diseases and the use of multiple concurrent medications on death anxiety within the context of sociodemographic characteristics. Material and Methods: This cross-sectional study included 324 individuals aged between 18-75 years who applied to Karabuk Community Health Center between November 2020 and February 2021. Twelve questions were asked to evaluate the socio-demographic characteristics of the participants. Participants' death anxiety levels were evaluated with the Turkish death anxiety scale consisting of 20 questions. The questionnaire and scale were applied to the participants by face-to-face interview technique. Results: The average age of the participants was 43.6113.27 years. The average death anxiety scale score of the individuals was found to be 47.0111.63. Individuals aged 51 and over, women with 2 or more children, those with hypertension and osteoporosis due to chronic diseases, and participants who use 4 or more drugs per day had significantly higher levels of death anxiety (p<0.05). Discussion: The death anxiety scale score obtained as a result of this study was found to be moderate. Organizing training on death anxiety, which impairs the quality of life of individuals, may positively affect individuals and cause them to become attached to life. Making the necessary changes to healthy lifestyles, early detection of common diseases and taking precautions, and avoiding multiple drug treatments as much as possible may be beneficial in increasing the quality of life and reducing death anxiety.Öğe The Frequency of Atopic Dermatitis and Other Skin Manifestations in Infants with Cow's Milk Protein Allergy in Karabuk, Turkey(Mashhad Univ Med Sciences, 2021) Dogan, Erkan; Sevinc, Eylem; Gamsizkan, Zerrin; Korkut, Burcu; Sevinc, NergizBackground Atopic dermatitis (AD) is the most common skin disease in childhood, and Cow's milk protein allergy (CMPA) is the most common cause of food allergies in infancy and may be characterized by atopic dermatitis with skin involvement as the first finding. The aim of this study is to determine the serum eosinophil cationic protein (sECP) levels, eosinophil counts and the frequency of AD and other skin manifestation among infants with CMPA. Materials and Methods: This cross-sectional study was conducted in Karabuk province, Turkey. Eighty-three infants who were diagnosed with CMPA and followed at the Karabuk Training Hospital Pediatric outpatient clinic. The first group consisted of 52 infants presenting with skin manifestations. The second group consisted of 31 infants who were not presenting skin manifestations. The sECP level of infants in both groups was measured using an Immulite 2000 XPi analyzer Immunoassay System (Germany). Results: Of 83 infants with CMPA, 62.6% (n=52) were detected skin involvement as the first finding. The proportions of atopic dermatitis and urticaria in CMPA infants with skin involvement were 90.4% and 9.6% respectively. The median sECP level and eosinophil counts (56.5 ng/mL vs 470/mm(3), p-value=0.001), in skin manifestations with CMPA group were significantly higher than that in the CMPA group without skin manifestations (33.1 ng/mL vs. 270/mm(3), p-value=0.006). Conclusion This study revealed that AD is the most common skin manifestation of CMPA and also found higher sECP levels in infants with skin involvement. The frequency of both diseases, which are easily treated with elimination diet, is increasing day by day.Öğe Healthy life-style behaviors and related factors among Turkish primary health care professionals(Marmara Univ, Fac Medicine, 2023) Oral, Belgin; Sevinc, Nergiz; Korkut, BurcuObjective: The role of health professionals working in primary care in providing services to all segments of society and in protecting and improving the health of all individuals is extremely important. The aim of this study is to determine the healthy lifestyle behaviors of primary health care workers in Karabuk city center and to examine some factors that may affect the choice of a healthy lifestyle.Materials and Methods: This cross-sectional study was conducted between October-December 2019 with the participation of 334 healthcare professionals in Karabuk. The questionnaire with 27 questions and the Healthy Lifestyle Behaviors Scale II (HLBS-II) were administered.Results: The median age of the health care workers participating in the study was 38.2 +/- 10.6. Of the participants 53.8% were women and approximately three-quarters of the participants (70.8%) were married. In terms of occupational groups, 10.9% of the participants were physicians, 25.0% were nurses and midwives, 16.7% were health officers/technicians and 47.4% were composed of other employees. The HLBS-II total score was found to be 126.8 +/- 21.3. The HLBS-II total score were higher in women, those who defined their health status as good, university graduates those who did not smoke, had good nutrition, exercised, and were satisfied with their body appearance.Conclusion: In our study, it was found that the healthy life behavior scores of health workers were at a good level. Especially men, smokers, high school graduates, obese, those who do not pay attention to their nutrition and physical activity should be informed and be supported by healthy living behavior programs.Öğe The Level of Knowledge and Awareness of Male University Personnels about Adult Cancers and Cancer Screening(Duzce Univ, Fac Medicine, 2021) Sevinc, Nergiz; Korkut, Burcu; Nacar, Erkay; Ozturk, ErdalObjective: Cancer incidence rates have been increasing for both genders. The first aim was to determine the knowledge level of men about the types of cancers on adults. The second aim was to assess the level of knowledge of them on cancer screening programs. Methods: This cross-sectional study was conducted at Karabuk University in 2020, with 312 males who worked as academicians, administrative personnel and contractlabor. A questionnaire on sociodemographic characteristics and the knowledge of male employees about cancer and cancer screenings was applied to the participants by interviewing in the university. Results: The mean age of male participants was 40 years. Of the participants, 39.7% knew that lung cancer is the most common type of cancer among men while 80.4% knew that breast cancer is the most common type of cancer among women. Of the participants, 42.9% heard of the Center of Early Detection and Screening of Cancer (CEDSC) and only 12.5% had a cancer screening test. The participants' answers to the question Which cancer screening tests are made in CEDSC? were breast cancer (55.8%), cervical cancer (35.6%), colorectal cancer (31.1%) and prostate cancer (26.0%). Mammography was the most well-known among screening tests (51.9%). The level of knowledge on colon, cervical and prostate cancer screening tests increased with age (p<0.05). Conclusions: The level of knowledge about cancer and cancer screenings of male participants was mostly moderate. It might be possible to increase the level of knowledge on cancer and cancer screening of men by preparing educative and informative programs.Öğe Low COVID-19-related practice increases the risk of poor health literacy in international students(Trisakti Univ, Fac Medicine, 2021) Sevinc, Nergiz; Korkut, BurcuBACKGROUND Health literacy (HL) is the ability to access, understand, appraise, and apply health information, making it crucial for navigating coronavirus and COVID-19 information environments. The objective of this study was to determine the health literacy of international students who could not return to their countries after announcement of the coronavirus disease (COVID-19) pandemic and their perspective and behavior about COVID-19. METHODS A cross-sectional study was conducted involving 399 international students. A 73-item questionnaire consisting of health literacy (23 items), knowledge, attitude and practice about Covid-19 (37 items), and sociodemographic characteristics (13 items) was answered by the students. The relationship between the HL score and various variables was determined using univariate and multiple binary logistic regression. RESULTS Of the 399 international students, 322 (80.7%) participated. The HL of the international students was found to be poor (78.0%) and good (22.0%). Participants' COVID-19-related behaviors: 8.4% of the participants' knowledge level was good, and 38.5% had high COVID-19 related practice. Multivariate models showed that HL was independently and significantly associated with COVID-19 related practice (OR= 6.27; 95% CI: 2.45 - 15.79; p=0.000). CONCLUSION This study revealed that international students' HL was poor and that low COVID-19 related practice increased the risk of low HL in international students. According to the findings, further efforts should be made to enhance levels of HL and COVID-19-related behavior of international students.Öğe Pre-Endoscopic viral screening of children during the Covid-19 pandemic(Bayrakol Medical Publisher, 2022) Dogan, Erkan; Sevinc, Eylem; Sevinc, Nergiz; Basar, ErhanAim: Transmission of SARS-CoV-2 infection can easily occur through direct or close contact with infected people, just as with other infectious diseases. Therefore, it is important to detect it prior to the intervention for protecting the health of both the healthcare worker and the patient. In the study, it was aimed to determine the seroposidvity rates of acute respiratory syndrome coronavirus 2, hepatitis A, hepatitis 8, hepatitis C virus and human immune deficiency virus infections among children who underwent gastrointestinal endoscopy. Material and Methods: The study was conducted at the Department of Pediatric Gastroenterology of the Karabuk University in Turkey from December 2020 to December of 2021. A total of 175 children were included in the study. The study was divided into three age groups as follows: 1-6 years old, 7-12 years old and 13-18 years old. All children were screened for acute respiratory syndrome coronavirus 2. hepatitis A, hepatitis B, hepatitis C virus and human immune deficiency virus infections. Results: The median age was 12.5 years (1-18). The seroprevalence of acute respiratory syndrome coronavirus 2, Anti-HAV IgM, Anti-HAV IgG, HBsAg, AntiHBs, Anti-HCV, Anti-HIV and were detected 0.57%, 0.57%, 42.8%, 0%, 58.8%. 1.1% and 0 % respectively. The seroprevalence of Anti-HAV IgG was significantly higher in children aged 1-6 years than in the group aged 13-18 years (95.7 vs 25.2: x2=48.1, p=0.001). Discussion: Although seroprevalence rates prior to endoscopy were low in this study, viral screening, except for hepatitis A infection, is essential for the safety of both patients and healthcare.Öğe Reduced levels of circulating natural killer cells in children with celiac disease(Indonesian Pediatric Soc Publishing House, 2020) Agin, Mehmet; Sevinc, Eylem; Dogan, Erkan; Sevinc, NergizBackground Celiac disease (CD) is an autoimmune disease characterized by malabsorption. Serologic testing for CD consists of Ig A type of antitissue transglutaminase (tTG), antiendomysium (EMA). These tests are helpful in monitoring adherence to the gluten-free diet (GFD). Natural killer (NK) cell count alterations have been reported in various diseases, such as cancer, Crohn's disease, malnutrition, and autoimmune disorders. Objective To compare peripheral blood NK cell counts in children with celiac disease (CD) to healthy controls. The second aim was to analyze for possible correlations between NK cells (CD3-/CD16+, CD56+) and tissue transglutaminase (tTG)- IgA and tTG-IgG, as well as endomysial antibody EMA-IgA indicating. gluten sensitivity. Methods Fifty children with CD were compared to 48 healthy children as controls, with similar age and sex distribution. Peripheral blood NK cell counts were measured by flow cytometry. Results The median (P25-P75) ages of the 50 celiac patients (23 male; 46%) and 48 controls (21 male; 44%) were 10 (2-17) years and 9 (3-17) years, respectively. Mean follow-up duration was 3 years, ranging from 1-10 years. All CD patients had positive tTG-IgA and EMA-IgA tests. while it was negative in all (100 %) control patients. The absolute number of circulating CD16+ NK cells (259.52 vs. 1404.36 mu/L) and CD56 + NK cells (366.24 vs. 2440.46 mu/L) were significantly lower in the celiac group than the control group (P<0.05 for both). The absolute numbers of circulating white blood cells (7785 vs. 8165 mu/L) and lymphocytes (3106 vs. 3173 mu/L) were not significantly different between the celiac and control groups (P>0.05 for both). Correlation analysis between the absolute number of circulating NK cells and tTG-IgA, tTG-IgG, and EMA-IgA levels in CD patients revealed no significant relationships (P>0.05 for all). Conclusions Peripheral blood NK cell count are significantly lower in celiac patients than controls, hence, decreased NK cell counts may be an abnormal feature seen in autoimmune diseases. NK cell count in celiac patients has no significant correlations to tTG-IgA, tTG-IgG, or EMA-IgA levels. Therefore, NK cell count may be inappropriate marker for monitoring compliance to a gluten free diet.Öğe Relationship of occupational health and safety training with health literacy among employees working in the various lines of business(Trisakti Univ, Fac Medicine, 2020) Sevinc, Nergiz; Korkut, BurcuBACKGROUND Health literacy is vital for people's ability to manage health. It has been known for a long time that the importance of education in increasing health literacy is an undeniable fact. The first aim of this study was to investigate the health literacy levels of employees working in different business lines receiving service from the occupational health and safety unit. The second aim was to reveal how health literacy levels are affected according to the training duration. METHODS A cross-sectional study was conducted on 202 employees receiving service from the Karabuk occupational health and safety unit. The employees were divided into three groups as workers, officers and others.All employees were given the questionnaire consisting of 31 questions including sociodemographic characteristics and the adult health literacy scale. A face-to-face interview was performed with each of the employees. Kruskal-Wallis H and Mann-Whitney U tests were used to analyze the data. RESULTS The range of adult health literacy scale scores of the employees was 4-23. There was no significant difference in adult health literacy scale scores between age groups (p=0.38). The percentage of employees who received more than 16 hours training course was 19.3%, 20.6%, and 46.7% for workers, civil servants and other employees, respectively. Adult health literacy scale scores increased in proportion to the amount of training the employees received (p=0.001). CONCLUSION This study reveals that occupational health training has a positive effect on health literacy.Öğe The Stigmatizing Effect of Tuberculosis Disease(Bayrakol Medical Publisher, 2022) Korkut, Burcu; Sevinc, NergizAim: This study aimed to measure the level of stigmatization using tuberculosis-related stigma (TRS) scale in healthy individuals and in patients with tuberculosis (TB) and to evaluate the factors affecting stigmatization. Material and Methods: This cross-sectional survey study included healthy individuals (aged 18-75 years) admitted to Community Health Centre and patients with TB (aged 18-75 years) admitted to Tuberculosis Control Dispensary in Karabuk City of Turkey between July 2021 and October 2021. A questionnaire consisting of two parts, in which the first part included questions about sociodemographic characteristics and the second part included questions of Tuberculosis-Related Stigma (TRS) scale for the assessment of level of stigmatization, was applied to both healthy individuals and patients with TB using a face-to-face survey technique. Results: The study included 360 healthy individuals (mean age: 45.46 +/- 12.90 years, female 65.3%) and 120 patients with TB (mean age, 41.15 +/- 16.42 years, male 60.8%). The mean total TRS scale score in healthy individuals was 18.60 +/- 4.18; those aged 36-53 years, those who were employed, and those living in the village had significantly higher TRS scale scores (p<0.05 for all). The mean total TRS scale score in TB patients was 19.72 +/- 3.20; those aged 18-35 years, single patients, those employed, and those with high- income level had significantly higher TRS scale scores (p<0.05 for all). Discussion: The current study revealed that the level of stigma was higher in patients with TB. Additionally, it was thought that preventing stigma in TB patients would positively affect the treatment process.
