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    Cochlear implantation due to ototoxic side effect of izoniazide
    (2016) Dündar, Yusuf; Saylam, Güleser; Özdek, Ali; Tatar, Emel; Korkmaz, Hakan
    Ototoxic side effects of many antineoplastic agentsand antibiotics have been reported, but there is notenough evidence about isoniaside. İsoniaside’s ototoxicside effect is mostly associated with end stage renalfailure. There is no much way except to cessation ofototoxic drug when ototoxic effects are seen. Cochlearimplantation is an important salvage option in bilateralsensorineural hearing loss. We are reporting a patientwho was developed sensorineural hearing loss andbilateral visual loss during anti-tuberculosis treatment.The last chance for communication was cochlearimplantation and it was performed with a successfuloutcome.
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    Does Diffusion-Weighted MR Imaging Change the Follow-Up Strategy in Cases with Residual Cholesteatoma?
    (Aves, 2015) Dundar, Yusuf; Akcan, Fatih Alper; Dilli, Alper; Tatar, Emel; Korkmaz, Hakan; Ozdek, Ali
    OBJECTIVE: To analyze the effectiveness of diffusion-weighted magnetic resonance imaging (DW-MRI) in the evaluation of recurrent cholesteatomas. MATERIALS and METHODS: Twenty-three patients undergoing second-look surgery were included in our study. There were 14 men and 9 women with ages ranging from 10 to 50. All patients underwent DW-MRI prior to second-look surgery. All magnetic resonance imaging (MRI) examinations were performed with a 1.5-T MRI unit using a standard 8-channel neurovascular coil. DW-MRI and apparent diffusion coefficient maps were included in the examination. Cholesteatoma was diagnosed on the DW-MRI as a marked hyperintense signal in comparison with brain tissue. All cases were classified as positive or negative. RESULTS: The sensitivity and specificity of DW-MRI were 86% and 87%, respectively. The positive predictive value of DW-MRI was 92%, while the negative predictive value was 77%. CONCLUSION: The DW-MRI technique is an important and effective technique in the evaluation of residual cholesteatoma. It can be an alternative method to second-look surgery, which can spare patients repeat operations.