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    General features of patients with Pulmonary Langerhans Cell Histiocytosis followed in our instution
    (Turkish Assoc Tuberculosis & Thorax, 2018) Acat, Murat; Tanriverdi, Elif; Ugur Chousein, Efsun Gonca; Demirkol, Baris; Yildirim, Binnaz Zeynep; Turan, Demet; Ozgul, Mehmet Akif
    Introduction: Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare disease affecting young smokers. It is more common between the ages of 20-40 and equals the male/female ratio. Lung biopsy is the most useful methods for diagnosis. The first treatment is to quit smoking. Corticosteroids or chemotherapeutic agents can be used in severe progressive cases despite of quiting smoking. The patients with PLCH followed in our clinic were assessed with general clinical features in the light of the literature. Materials and Methods: We retrospectively evaluated patients with PLCH in our clinic between January 1999 and June 2017. Results: The female and male distribution of the 21 patients was 11/10. The average age was 35.04 +/- 11.78 years. All patients were active smokers at the time of admission. The most common symptom was dyspnea. The most common finding in the pulmonary function tests was obstructive ventilatory defect. The DLCO value of the 70% patient in the carbonmonooxid diffusion test was below 80%. The most common pathologic findings detected in high-resolution chest tomography (HRCT) were cystic lesions involving bilateral upper and middle areas. There were 3 (14%) patients with pneumothorax at the time of admission and 6 (28.5%) patients with pneumothorax history before. The most common diagnostic method was open lung biopsy. All the patients quit cigarette after the diagnosis. There were 6 patients using steroid therapy, 1 patient receiving steroid and bosentan therapy, and 1 patient made pleurectomy due to recurrent pneumothorax. Lung transplantation was done to patient who received combined bosentan treatment with steroids. Conclusion: PLCH is a rare disease and should be considered in young, smokers with spontaneous pneumothorax and cystic lung disease in the differential diagnosis. As more diffusions are affected in patients, respiratory functions for follow-up should be evaluated with diffusion tests. It is essential to quit smoking in therapy.
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    Oki stent application in different indications: Six cases
    (Wiley, 2018) Ozgul, Mehmet Akif; Cetinkaya, Erdogan; Cortuk, Mustafa; Tanriverdi, Elif; Yildirim, Binnaz Zeynep; Balci, Merih Kalamanoglu; Issaka, Adamu
    IntroductionWe have used Oki stents for a number of different indications. After discovering that there are limited reports in the literature on these stents, we were motivated to share our experiences in Oki stenting. ObjectivesWhile there is vast knowledge on double Y-stents, the Oki stent is a relatively recent development in pulmonology. Here, we demonstrate that stenting of the right secondary carina using an Oki stent should be considered for obstructions in this region. MethodsWe placed 13 mm x 10 mm x 9 mm Oki stents in six patients under general anesthesia via rigid bronchoscopy. ResultsThree cases were post-transplant patients with malacia, stenosis, and bronchopleural fistula. One case had an airway obstruction due to malignant disease, another case had a right aortic arc and aberrant left subclavian artery anomaly, and the final case had bronchopleural fistula. No serious complications were observed during stent placement. ConclusionsOki stents can safely be used for many clinical conditions. Patients benefit greatly from stenting; however, two of our cases died due to infection, and one case died due to malignancy.