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    Morphometric examination of the hepatobiliary duct system in healthy individuals and patients with cholelithiasis: A radio-anatomic magnetic resonance cholangiopancreatography study
    (Cukurova Univ, Fac Medicine, 2023) Toy, Seyma; Senol, Deniz; Ciftci, Rukiye; Sevgi, Serkan; Secgin, Yusuf; Yildirim, Ismail Okan
    Purpose: Cholelithiasis is a common gallbladder disease with high morbidity and treatment cost. Although the disease has many formation factors such as bile duct obstruction, congenital anomalies, genetic and metabolic diseases, the main cause is gallstones. The aim of this study is to examine the radio-anatomic and demographic characteristics of the bile ducts of patients who have cholelithiasis due to gallstones by using magnetic resonance cholangiopancreatography (MRCP) and to compare with healthy individuals.Materials and Methods: The study was carried out by retrospectively scanning the MRCP images of 113 patients diagnosed with cholelithiasis and 87 healthy individuals who were referred to the hospital for various indications and had no gallbladder pathology. Results: According to the Spearman rho correlation test performed by ignoring gender, a significant correlation was found between right hepatic duct diameter (RHD-D) and right hepatic duct - cystic duct angle (RHDCD-A), and between left hepatic duct diameter (LHD-D) and common bile duct diameter (CBD-D). In the correlation analysis performed only among males, a significant correlation was found between RHDCD-A and right hepatic duct - left hepatic duct angle (RLHD-A), RHDCD-A and common hepatic duct diameter (CHD-D) parameters. In the correlation analysis performed only among women, a significant relationship was found between age and RHD-D, LHD-D, CHD-D, CBD-D, between RHDCD-A and cystic duct - gallbladder angle (CDG-A), RHD-D, and between CHD-D and cystic duct diameter (CD-D).Conclusion: This study will contribute to literature by revealing the morphometric characteristics and radio -anatomic information of the hepatobiliary systems of both patients with cholelithiasis and healthy individuals.
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    Morphometric Examinations of Internal Carotid Arteries of Patients with Hypertension and Patients with Type 2 Diabetes Mellitus: A Radio Anatomic Study Based on Computed Tomography Angiography Findings
    (Turkish Neurosurgical Soc, 2022) Ciftci, Rukiye; Ulubaba, Hilal Er; Senol, Deniz; Toy, Seyma; Yildirim, Ismail Okan
    AIM: To examine the relationship between the morphologic features of the internal carotid artery (ICA) and symptoms affecting cerebral blood circulation including type 2 diabetes mellitus (T2DM) and hypertension (HT).MATERIAL and METHODS: In this study, retrospective morphometric analysis of ICA measurements from 100 patients (aged 45-60 years) was performed using computed tomographic angiography (CTA) images. The images were divided into four groups: patients with HT (group 1), patients with T2DM (group 2), patients with HT and T2DM (group 3), and a healthy control group (group 4). Length and diameter measurements of the cervical, petrous, cavernous, and terminal segments of the ICA were made using 3D CTA images and recorded. The measurements of the male and female patients were compared using the Mann-Whitney U test and the groups were compared using the Kruskal-Wallis H test.RESULTS: It was found that there were statistically significant differences between male and female patients in terms of the right and left petrous, cavernous, and terminal segments of the ICA in group 1, right and left cervical left cavernous in group 3, left cervical, right and left petrous, cavernous, and right cavernous in group 4 (p<0.05). According to the Kruskal-Wallis H test analysis results, it was determined that there were no statistically significant differences between the patients in the four groups for all segment measurements (p>0.05).CONCLUSION: It was determined that ICA was more affected by HT than diabetes. In addition, we think that being knowledgeable of morphometric measurements of ICA will guide radio-anatomic evaluations and increase the level of microanatomic knowledge in surgical treatment.