Effects of Preemptive Single Dose Sustained Release NonSteroidal Anti- Inflammatory Drugs on Postoperative Complications Following Third Molar Surgery

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dc.authoridKasapoglu, Metin Berk/0000-0003-3325-523X
dc.authoridCebi, Ahmet Taylan/0000-0001-9083-7215
dc.contributor.authorCebi, Ahmet Taylan
dc.contributor.authorKasapoglu, Metin Berk
dc.date.accessioned2024-09-29T16:06:39Z
dc.date.available2024-09-29T16:06:39Z
dc.date.issued2021
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to compare the effectiveness of two preemptive sustained-release non-steroidal anti- inflammatory drugs in terms of pain, edema and trismus following third molar surgery. Methods: Overall, 30 patients with double-sided vertically positioned impacted third molars were included in this study. The study was randomized and double- blinded. 30 minutes before the surgery, patients were given sustained-release (SR) dexketoprofen trometamol 75 mg and following the surgery the drug administration continued postoperatively for 1 week, once a day. 2 weeks later, the same procedure was applied for the counterside impacted third molar with 75 mg. sustained-release (SR) diclofenac sodium. The pain was assessed postoperatively by VAS (Visual Analogue Scale) levels at the 6th, 8th, 12th, 24th and 48th hours and on the 3rd, 5th, and 7th days. Edema and trismus measurements were evaluated on the postoperative 2nd and 7th days. Results: There was a statistically significant difference between the groups in VAS levels at 6th, 8th, 12th, 24th, and 48th hours, and on the 3rd and 5th days (P <0.01). Dexketoprofen trometamol SR group had lower VAS levels than diclofenac sodium SR group. There was no statistically significant difference between the groups in terms of mean trismus and edema measurement on the 2nd and 7th days (P<0.05). Conclusions: Dexketoprofen trometamol SR and diclofenac sodium SR are similarly effective for the reduction of edema and trismus following impacted third molar surgery; however, dexketoprofen trometamol SR is found to be more efficient in reducing pain.en_US
dc.identifier.doi10.18521/ktd.772556
dc.identifier.endpage88en_US
dc.identifier.issn1309-3878
dc.identifier.issue1en_US
dc.identifier.startpage82en_US
dc.identifier.trdizinid427837en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.772556
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/427837
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6957
dc.identifier.volume13en_US
dc.identifier.wosWOS:000628768700013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDuzce Univen_US
dc.relation.ispartofKonuralp Tip Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThird Molaren_US
dc.subjectPostoperative Complicationsen_US
dc.subjectSustained-Release Preparationsen_US
dc.subjectNonsteroidal Anti-Inflammatory Agentsen_US
dc.titleEffects of Preemptive Single Dose Sustained Release NonSteroidal Anti- Inflammatory Drugs on Postoperative Complications Following Third Molar Surgeryen_US
dc.typeArticleen_US

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