Effect of Continuous Positive Airway Pressure Treatment on Mean Platelet Volume and Platelet Distribution Width in Patients with Sleep Apnea Syndrome

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dc.authoridBAYAR MULUK, NURAY/0000-0003-3602-9289
dc.authoridCortuk, Mustafa/0000-0002-6923-736X
dc.authoridOzel, Gokce/0000-0001-5281-0986
dc.contributor.authorCortuk, Mustafa
dc.contributor.authorSimsek, Gokce
dc.contributor.authorKiraz, Kemal
dc.contributor.authorHaytoglu, Suheyl
dc.contributor.authorZitouni, Burcak
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorArikan, Osman Kursat
dc.date.accessioned2024-09-29T16:09:40Z
dc.date.available2024-09-29T16:09:40Z
dc.date.issued2016
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: Obstructive sleep apnea (OSA) syndrome is a common disorder that can cause hypercoagulation. Mean platelet volume (MPV) and platelet distribution width (PDW) are associated with hypercoagulability. This study aimed to investigate whether MPV and PDW values change in patients with OSA who were treated with continuous positive airway pressure (CPAP) device. Methods: A total of 43 adult patients with OSA who were treated with CPAP were included in this retrospective study. Patients who underwent CPAP treatment for <5 days/week and <4 h/day were excluded. Blood parameters, including MPV and PDW, were recorded before CPAP treatment and at the third month of CPAP treatment. All patients underwent polysomnographic evaluation with full night polysomnography and in the second night CPAP titration was performed together with full night polysomnography and MPV and PDW values were statistically compared before and after CPAP treatment. Results: Apnea hypopnea index was significantly reduced, whereas oxygen saturation was significantly increased at CPAP titration night (p<0.001). The third month of CPAP treatment resulted in significantly low PDW (p=0.004) values, but MPV values did not change. Conclusion: PDW value at the third month of CPAP treatment revealed a significant improvement compared with the values before treatment; moreover, no change was observed in MPV values. It was concluded that in patients with OSA who were treated with CPAP, activation of platelets may result in recovery.en_US
dc.identifier.doi10.5152/ejp.2016.84803
dc.identifier.endpage89en_US
dc.identifier.issn2148-3620
dc.identifier.issn2148-5402
dc.identifier.issue2en_US
dc.identifier.startpage85en_US
dc.identifier.urihttps://doi.org/10.5152/ejp.2016.84803
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7711
dc.identifier.volume18en_US
dc.identifier.wosWOS:000382875700005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofEurasian Journal of Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCPAP treatmenten_US
dc.subjectobstructive sleep apneaen_US
dc.subjectplatelet activationen_US
dc.subjectplatelets mean platelet volumeen_US
dc.titleEffect of Continuous Positive Airway Pressure Treatment on Mean Platelet Volume and Platelet Distribution Width in Patients with Sleep Apnea Syndromeen_US
dc.typeArticleen_US

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