The prognostic role of platelet to lymphocyte ratio and mean platelet volume in critically ill patients

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dc.authoridBenli, Ali Ramazan/0000-0003-0039-1497
dc.authoridYILDIZ, Abdulkerim/0000-0002-9596-4042
dc.contributor.authorYildiz, A.
dc.contributor.authorYigit, A.
dc.contributor.authorBenli, A. R.
dc.date.accessioned2024-09-29T16:11:36Z
dc.date.available2024-09-29T16:11:36Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractOBJECTIVE: The aim of this study was to identify the relationship between complete blood count parameters, mean platelet volume (MPV), and platelet to lymphocyte ratio (PLR) with mortality and hospitalization duration in critically ill patients. PATIENTS AND METHODS: A retrospective analysis was made of patients admitted to our tertiary adult intensive Care Unit (ICU) between January 2015 and January 2016. Hemoglobin (Hb), white blood cell (WBC), lymphocyte and platelet counts were obtained from the complete blood count performed at the time of admission. MPV and PLR levels were calculated from these data. Other data were retrieved from the patient follow-up records. RESULTS: The investigation included a total of 306 patients. The total mortality rate was 40.2%. The initial median PLR level was 206.7 (8.1-1675.0) for non-survivor patients and 194.5 (12.8-1236.6) for survivor patients. The PLR level was higher in the non-survivor group, but there was no statistically significant difference between the groups (p>0.05). The median MPV level was 7.66 (5.17-15.25) for the survivors and 8.09 (4.36-16.19) for the non-survivors, and there was no statistically significant difference between the groups (p=0.237). The median length of stay (LOS) of all patients was 7 (2-61) days. Only the Acute Physiology and Chronic Health Evaluation (APACHE) II score was found to have a positive correlation with LOS (p<0.05). CONCLUSIONS: PLR has no effect on mortality rates regardless of whether the patient has thrombocytopenia or not at the time of admission. MPV levels have no significant relationship with mortality. Neither MPV nor PLR have an effect on LOS. The use of these as a prognostic factor for mortality in critically ill patients is still unclear.en_US
dc.identifier.endpage2252en_US
dc.identifier.issn1128-3602
dc.identifier.issue8en_US
dc.identifier.pmid29762825en_US
dc.identifier.startpage2246en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14619/8545
dc.identifier.volume22en_US
dc.identifier.wosWOS:000432375900010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlatelet to lymphocyte ratioen_US
dc.subjectMean platelet volumeen_US
dc.subjectCritically ill patientsen_US
dc.subjectMortalityen_US
dc.titleThe prognostic role of platelet to lymphocyte ratio and mean platelet volume in critically ill patientsen_US
dc.typeArticleen_US

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