Cancer is seen more in older female patients with psoriasis : a cross-sectional study in 1551 patients
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Tarih
2019
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The aim of this study was to establish the potential risk of the development of malignancy in the patients with psoriasis.Material and Methods: A retrospective analysis of psoriasis cases between January 2017 to August 2018 attending the dermatologyclinic at Karabuk Research and Training Hospital was carried out. Patients with psoriasis were screened whether they have anymalignant disease and associated chronic disease including diabetes mellitus and hypertension by using hospital data system.Suspected cases regarding psoriasis or malignant disease were excluded. Findings were compared according to demographiccharacteristics of the patients.Results: A total of 1551 patients with psoriasis was evaluated in the study time. 30 patients (22 women, 8 men) were found to havemalignancy. The most commonly seen malignancy was stomach cancer in women and prostate cancer in men. 2% of patients withpsoriasis had cancer. This rate was 2.5% in female patients and 1% in male patients (p <0.005). The mean age of psoriatic patientswith cancer was 58.3 years , higher than 41.9 years which is the mean age of all psoriasis patients in the study (p <0.005). The cancercases were more common in psoriasis patients having diabetes and/or hypertension in comparison with those without diabetesand/or hypertesion (p <0.005).Conclusion: Cancer was found to be more common in female patients with psoriasis particularly in older age group. In addition,diabetes and hypertension have significant contribution to occurrence of the malignancy in patients with psoriasis.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
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Cilt
26
Sayı
5
