Serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus

Basit Öğe Kaydı
dc.contributor.authorYılmaz, Ümit
dc.contributor.authorBurlukkara, Salih
dc.contributor.authorDemir, Demirhan Orsan
dc.date.accessioned2024-12-26T12:17:46Z
dc.date.available2024-12-26T12:17:46Z
dc.date.issued2024
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractThis study was designed to determine the serum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus (T2DM). A total of 154 individuals aged 30-60 were included in the study and the participants were divided into three groups: D-ED group (individuals with T2DM and ED) (n=49), ND-ED group (individuals with ED without T2DM) (n=55), and control group (individuals without T2DM and ED) (n=50). The age, BMI, and IIEF-5 score were recorded for all participants. The HDL, LDL, triglycerides, cholesterol, HbA1c and testosterone were determined from the blood taken from the participants, and galanin and relaxin-3 levels were measured in serum samples by ELISA method. The IIEF-5 score of the D-ED group was statistically lower than that of the ND-ED and control groups, and the IIEF-5 score of the ND-ED group was also lower than that of the control group. Serum testosterone levels in the control group were statistically higher than in the D-ED and ND-ED groups. The galanin level of the D-ED group was elevated than the control and ND-ED groups, but the galanin level of the ND-ED group was lower than the control group. The relaxin-3 levels were decreased in the D-ED and ND-ED groups compared to the control group. Galanin levels increased in individuals with T2DM and ED, however decreased in individuals with ED without T2DM. In addition, reduced relaxin-3 level may play a role in the development of ED.
dc.identifier.doi10.5455/medscience.2024.07.077
dc.identifier.endpage666
dc.identifier.issue3
dc.identifier.startpage661
dc.identifier.trdizinid1282496
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1282496
dc.identifier.urihttps://hdl.handle.net/20.500.14619/14893
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectErectile dysfunction
dc.subjectType 2 diabetes mellitus
dc.subjectTestosterone
dc.subjectIIEF-5
dc.subjectgalanin
dc.subjectRelaxin-3
dc.titleSerum relaxin-3 and galanin levels in individuals with erectile dysfunction with and without type 2 diabetes mellitus
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
1179379_1735215489.pdf
Boyut:
377.36 KB
Biçim:
Adobe Portable Document Format
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Tıp Fakültesi Koleksiyonu