The effect of different forms of intravitreal ranibizumab administration on pain

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dc.contributor.authorCoşkun, Mehmet
dc.date.accessioned2024-09-29T16:32:06Z
dc.date.available2024-09-29T16:32:06Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractAim: To examine the effect of using the prefilled syringe formulation of intravitreal ranibizumab (ivr) on pain. Materials and Methods: 30 patients received bilateral IVR injection due to diabetic retinopathy and macular edema and 30 eyes of these patients that received ready-to-use (PFS) IVR were considered as group 1, and the 30 eyes that received conventional IVR by withdrawing from the vial were considered as group 2. Patients who had previously received intravitreal injection, had intraocular surgery, used any eye drops, and were unable to cooperate with the assesment were excluded from the study. Pain experienced during the injection was assessed by using the numerical rating scale (NRS) and the verbal rating scale (VRS). Results: The mean age of 30 female patients evaluated was 60.3±7.94 years. While the NRS was 3.70±0.79 in Group 1, it was 4.23±0.77 in Group 2, the difference was statistically significant (p = 0.02). While the VRS was 2.13±0.34 in Group 1, it was found to be 3.0±0.58 in Group 2, the difference was statistically significant (p =0.02). Conclusion: IVR application in ready-to-use formulation causes less pain during intravitreal injection.en_US
dc.identifier.doi10.5455/annalsmedres.2024.03.064
dc.identifier.endpage458en_US
dc.identifier.issue6en_US
dc.identifier.startpage456en_US
dc.identifier.trdizinid1243894en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2024.03.064
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1243894
dc.identifier.urihttps://hdl.handle.net/20.500.14619/11363
dc.identifier.volume31en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorCoşkun, Mehmet
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effect of different forms of intravitreal ranibizumab administration on painen_US
dc.typeArticleen_US

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