Medical and advanced heart failure therapies in Türkiye

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dc.authoridhttps://orcid.org/0000-0002-9798-9796
dc.authoridhttps://orcid.org/0000-0001-7552-8967
dc.authoridhttps://orcid.org/0000-0002-9417-7610
dc.authoridhttps://orcid.org/0000-0002-2227-6177
dc.authoridhttps://orcid.org/0000-0001-6947-2821
dc.authoridhttps://orcid.org/0000-0002-8169-8628
dc.authoridhttps://orcid.org/0000-0003-3416-5965
dc.authoridhttps://orcid.org/0000-0003-0224-1433
dc.authoridhttps://orcid.org/0000-0003-0825-1851
dc.authoridhttps://orcid.org/0000-0002-7068-1599
dc.authoridhttps://orcid.org/0000-0002-7828-9487
dc.authoridhttps://orcid.org/0000-0002-4027-9873
dc.authoridhttps://orcid.org/0000-0002-3935-0222
dc.authoridhttps://orcid.org/0000-0001-8104-6198
dc.contributor.authorNalbantgil, Sanem
dc.contributor.authorDemir, Emre
dc.contributor.authorÇelik, Ahmet
dc.contributor.authorÇöllüoğlu, İnci Tuğçe
dc.contributor.authorAta, Naim
dc.contributor.authorYilmaz, Mehmet Birhan
dc.contributor.authorYilmaz, Mehmet Birhan
dc.contributor.authorKanik, Emine Arzu
dc.contributor.authorAsarcikli, Lale Dinç
dc.contributor.authorÇavuşoğlu, Yüksel
dc.date.accessioned2025-03-03T08:12:23Z
dc.date.available2025-03-03T08:12:23Z
dc.date.issued2024-05-07
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground/aim: Effective management of heart failure involves evidence-based use of multiple medications and their combinations. Furthermore, dosage escalation of the recommended medications is advised. In cases of advanced heart failure, long-term mechanical assistance devices or heart transplantation surgery may be necessary. Socio-economic disparities create unequal opportunities for people to access these treatments. The study aimed to analyze and compare medical and advanced heart failure treatments recommended by guidelines across various regions in Türkiye. Materials and methods: About 85 million citizens medical treatment records were utilized between January 1, 2016, and December 31, 2022. Medical and heart replacement treatment opportunities for heart failure in Türkiye were evaluated in the general population and across different geographical regions. Results: According to this study, beta-blockers were the most commonly prescribed medication for heart failure in Türkiye. This was followed by angiotensin-converting enzyme inhibitors at 44% and mineralocorticoid receptor antagonists at 38.9%. However, only 0.6% of patients used angiotensin receptor blocker-neprilysin inhibitors. Despite the high incidence of diabetes mellitus among heart failure patients, only 11% used sodium-glucose cotransporter two inhibitors. The study also found that using an implantable cardioverter defibrillator (ICD) was 0.8%, and cardiac resynchronization therapy (CRT) was 0.3% among all intracardiac device treatments. Heart replacement therapies, cardiac transplantation surgery, and long-term left ventricle-assisted device (LVAD) surgery had very low rates. Conclusion: The use of guideline-directed medical therapy is not optimal in Türkiye and varies across different geographical regions. It is a fact that heart transplant or LVAD surgery, CRT, and ICD implantation rates in Türkiye are significantly lower than those in developed countries, regardless of geographical region.
dc.identifier10.55730/1300-0144.5933
dc.identifier.citationNalbantgil, S., Demir, E., Çelik, A., Çöllüoğlu, İ. T., Ata, N., Yilmaz, M. B., Şahin, A., Ural, D., Ülgü, M. M., Kanik, E. A., Asarcikli, L. D., Çavuşoğlu, Y., Murat, S., & Birinci, Ş. (2024). Medical and advanced heart failure therapies in Türkiye. Turkish journal of medical sciences, 54(7), 1470–1477. https://doi.org/10.55730/1300-0144.5933
dc.identifier.doi10.55730/1300-0144.5933
dc.identifier.endpage1477
dc.identifier.issn1300-0144
dc.identifier.issue7
dc.identifier.other1303-6165
dc.identifier.pmid39735483
dc.identifier.scopus2-s2.0-85213385126
dc.identifier.scopusqualityQ1
dc.identifier.startpage1470
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5933
dc.identifier.urihttps://hdl.handle.net/20.500.14619/15099
dc.identifier.volume54
dc.identifier.wosWOS:001381273000007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherTUBITAK
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.ispartofseriesTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDevice therapy
dc.subjectheart failure
dc.subjectmedical therapy
dc.subjectnationwide study
dc.titleMedical and advanced heart failure therapies in Türkiye
dc.typeArticle
oaire.citation.issue7
oaire.citation.volume54

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