Fragmented QRS is associated with subclinical left ventricular dysfunction in patients with chronic kidney disease

Basit Öğe Kaydı
dc.authoridOkutucu, Sercan/0000-0002-2001-929X
dc.authoridOnalan, Orhan/0000-0001-9780-7051
dc.contributor.authorAdar, Adem
dc.contributor.authorKiris, Abdulkadir
dc.contributor.authorUlusoy, Sukru
dc.contributor.authorOzkan, Gulsum
dc.contributor.authorBektas, Huseyin
dc.contributor.authorOkutucu, Sercan
dc.contributor.authorOnalan, Orhan
dc.date.accessioned2024-09-29T16:03:02Z
dc.date.available2024-09-29T16:03:02Z
dc.date.issued2014
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective We aimed to investigate the association of fragmented QRS (fQRS) with subclinical left ventricular (LV) dysfunction in patients with chronic kidney disease (CKD). Methods and results Patients with CKD who had a normal LV ejection fraction (>= 50%) were enrolled. The tissue Doppler-derived Tei index was measured for all patients. A Tei index of >= 0.5 was considered abnormal. Subclinical LV dysfunction was defined as the presence of an abnormal Tei index in the absence of impaired LV ejection fraction (< 50%). The fQRS was defined as the presence of an additional R wave (R') or notching of R or S wave or the presence of fragmentation in two contiguous ECG leads. The study group consisted of 82 patients (45 male, mean age 54 14 years). Overall, prevalence of fQRS was 60% among CKD patients who had a preserved LV ejection fraction. Of these, 52 (63%) had an abnormal (>= 0.5) and 30 (37%) a normal Tei index (< 0.5). The prevalence of fQRS was significantly higher in patients with an abnormal Tei index than in patients with a normal Tei index (71% vs. 40%, P = 0.006). Patients with an abnormal Tei index had a lower E/A ratio as compared to patients with a normal Tei index (P = 0.03). Groups were similar with respect to all other variables. In multivariate logistic regression analysis, the presence of fQRS was independently associated (OR 3.52, 95% CI 1.28-9.64) with the presence of an abnormal Tei index after adjustment for potential confounders. Conclusion Fragmented QRS is independently associated with subclinical LV dysfunction in patients with CKD and normal ejection fraction.en_US
dc.identifier.doi10.1080/AC.69.4.3036654
dc.identifier.endpage390en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue4en_US
dc.identifier.pmid25181913en_US
dc.identifier.startpage385en_US
dc.identifier.urihttps://doi.org/10.1080/AC.69.4.3036654
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5851
dc.identifier.volume69en_US
dc.identifier.wosWOS:000346681400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic kidney diseaseen_US
dc.subjectfragmented QRSen_US
dc.subjectleft ventricular dysfunctionen_US
dc.titleFragmented QRS is associated with subclinical left ventricular dysfunction in patients with chronic kidney diseaseen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu