Adenovirus 36 and its effect on vitamin D levels in obese and overweight patients

Basit Öğe Kaydı
dc.contributor.authorCakmakliogullari, Elcin Kal
dc.contributor.authorSevencan, Nurhayat Ozkan
dc.date.accessioned2024-09-29T16:08:18Z
dc.date.available2024-09-29T16:08:18Z
dc.date.issued2019
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIntroduction: The aim of this study was to investigate the prevalence of Adenovirus-36 (Ad-36) in overweight and obese patients and the effects of this virus on some metabolic parameters. Methodology: The study included 236 female patients with body mass index (BMI) >= 25. The patients were separated into 2 groups as overweight (BMI: 25-29.99) and obese (BMI >= 30). To quantitatively determine the antibody (Ab) specific to adenovirus type 36 in the serum samples, the enzyme-immunoassay (EIA) method was used (AdV36-Ab, ELISA Kit, MyBioSource). Laboratoryparameters were compared between patients who are Ad-36 Ab positive and negative. Results: Of the total 236 patients, 82 (34.7%) were determined as Ad-36 positive and 154 (65.3%) were negative. Ad-36 Ab positivity was statistically significantly higher in the obese group (p = 0.018). The HOMA-IR index, triglyceride, total cholesterol, high-density lipoprotein, and low-density lipoprotein were found to be the same in both groups with no statistically significant differences(p > 0.05). Vitamin D levels were significantly higher in BMI >= 30 Ad-36 Ab positive group than negative group (p < 0.05). Conclusion: The frequency ofAd-36 Ab positivity was significantly higher in the obese group than in the overweight group. These results can be considered to shed a different perspective from previous reports in literature as only overweight and obese females were included. To the best of our knowledge, this study is the first to have shown that Ad-36 has the effect of elevating the Vitamin D levels.en_US
dc.identifier.doi10.3855/jidc.11285
dc.identifier.endpage670en_US
dc.identifier.issn1972-2680
dc.identifier.issue7en_US
dc.identifier.pmid32065825en_US
dc.identifier.startpage665en_US
dc.identifier.urihttps://doi.org/10.3855/jidc.11285
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7473
dc.identifier.volume13en_US
dc.identifier.wosWOS:000487585400011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Infection Developing Countriesen_US
dc.relation.ispartofJournal of Infection in Developing Countriesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdenovirus-36en_US
dc.subjectobesityen_US
dc.subjectbody mass indexen_US
dc.subjectvitamin Den_US
dc.titleAdenovirus 36 and its effect on vitamin D levels in obese and overweight patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu