Predictors of neck metastasis in early stage oral cavity cancer

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dc.contributor.authorErtugrul, Suha
dc.contributor.authorErtugrul, Goksen
dc.contributor.authorImre, Abdulkadir
dc.contributor.authorPinar, Ercan
dc.contributor.authorCalli, Caglar
dc.contributor.authorCalli, Aylin Orgen
dc.contributor.authorOncel, Semih
dc.date.accessioned2024-09-29T16:06:54Z
dc.date.available2024-09-29T16:06:54Z
dc.date.issued2015
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: To identify the effects of clinical and histopathological parameters on neck metastasis in early-stage oral cavity cancers. Methods: The medical records of 92 patients who underwent primary surgical resection and concurrent neck dissection due to early-stage oral cavity squamous cell cancer at Izmir Aatiirk Training and Research Hospital between June 2001 and June 2010 were retrospectively reviewed. The associations of clinical and histological parameters with neck metastasis were assessed. Based on the histological data, the histological sections of the operative tissue were obtained via the measurement of tumor width and tumor depth. Using an optical micrometer, the maximum width at the horizontal plane and the maximum depth at the vertical plane were measured and the maximum depth was recorded as tumor thickness. Results: The association between neck metastasis and tumor localization, T stage, degree of differentiation, tumor thickness, perineural invasion, vascular invasion and perilymphatic invasion in early-stage oral cavity cancers was found statistically significant (p<0.05). The value of critical tumor thickness for the neck metastasis was found to be 5.6 mm. Conclusion: On the basis of our results, a tumor thickness of 5.6 mm is the critical value for the development of neck metastasis in oral cavity cancers. The neck metastasis risk showed a significant increase in cases where the tumor thickness exceeded this threshold value. In oral cavity cancers with a high risk of occult metastasis, the tumor thickness may be identified pre-operatively or intra-operatively and, a decision can be taken to perform neck dissection when they exceed critical values.en_US
dc.identifier.doi10.2399/jmu.2015002007
dc.identifier.endpage86en_US
dc.identifier.issn2149-7109
dc.identifier.issn2149-6498
dc.identifier.issue2en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.2399/jmu.2015002007
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7122
dc.identifier.volume5en_US
dc.identifier.wosWOS:000366675100007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDeomed Publ, Istanbulen_US
dc.relation.ispartofEnt Updatesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeck metastasisen_US
dc.subjectoral cavity canceren_US
dc.subjecttumor thicknessen_US
dc.titlePredictors of neck metastasis in early stage oral cavity canceren_US
dc.typeArticleen_US

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