The Role of Relative Troponin Change in Predicting Clinical Outcome and Critical Stenosis in Patients with Chest Pain

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dc.authoridAtis, Seref Emre/0000-0002-5094-6000
dc.authoridCekmen, Bora/0000-0003-3348-8375
dc.authoridBozan, Oner/0000-0002-4195-2601
dc.contributor.authorAtis, Seref Emre
dc.contributor.authorKoseoglu, Zikret
dc.contributor.authorCekmen, Bora
dc.contributor.authorBozan, Oner
dc.contributor.authorKarcioglu, Ozgur
dc.date.accessioned2024-09-29T16:08:30Z
dc.date.available2024-09-29T16:08:30Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractAim: Dynamic changes in troponin levels have been shown to be effective indicators of acute injury and useful for distinguishing acute injuries from chronic injuries. This study investigates the role of the change in troponin I (TnI) values in the prediction of acute myocardial infarction (AMI) and its relationship with the findings of percutaneous coronary angiographies. Materials and Methods: The patients included here were divided into two groups: a group of patients with AMI and a group of patients without AMI. The patients diagnosed with AMI were subsequently divided into two subgroups as those with and without critical stenosis. The relative troponin change in these patients was calculated as the percentage of the difference between the first and second troponin measurements; the second measurement was taken two hours later after admission. Results: The receiver operating curve analysis revealed that increases of more than 83.18% in Delta TnI were significant predictors of AMI and critical stenosis [sensitivity 45.24%, specificity 89.67%, area under the curve (AUC)=0.698 (95% confidence interval (CI): 0.639-0.752, p=0.001), sensitivity 56.00%, specificity 87.92%, AUC value of 0.681 (95% CI: 0.620-0.738, p<0.001), respectively]. Conclusion: The Delta TnI value is a useful marker with high negative and positive predictive values for detecting AMI in patients admitted with chest pain. It can be beneficial as an adjunctive tool to predict the critical lesion, in conjunction with percutaneous angiography.en_US
dc.identifier.doi10.4274/eajem.galenos.2022.47135
dc.identifier.endpage221en_US
dc.identifier.issn2149-5807
dc.identifier.issn2149-6048
dc.identifier.issue3en_US
dc.identifier.startpage215en_US
dc.identifier.trdizinid1124624en_US
dc.identifier.urihttps://doi.org/10.4274/eajem.galenos.2022.47135
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1124624
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7594
dc.identifier.volume21en_US
dc.identifier.wosWOS:000855521100010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofEurasian Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTroponinen_US
dc.subjectacute myocardial infarctionen_US
dc.subjectchest painen_US
dc.subjectcoronary stenosisen_US
dc.subjectoutcomeen_US
dc.titleThe Role of Relative Troponin Change in Predicting Clinical Outcome and Critical Stenosis in Patients with Chest Painen_US
dc.typeArticleen_US

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