Additional preoperative parameters to enable the decision of partial orchiectomy in small testicular masses

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dc.contributor.authorSelvı, İsmail
dc.contributor.authorBasar, Halil
dc.date.accessioned2024-09-29T16:29:05Z
dc.date.available2024-09-29T16:29:05Z
dc.date.issued2020
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: We aimed to determine the predictive value of additional parameters for differentiating benign-malign tumors and to identify optimal patients for partial orchiectomy in unilateral, small (?2 cm) testicular masses.Methods: The data of 31 patients who underwent radical orchiectomy between January 2010 and December 2017 due to unilateral and small testicular masses were retrospectively analyzed. Demographic data, histopathological tumor types, serum tumor markers, neutrophil/lymphocyte ratio (NLR), monocyte/ lymphocyte ratio (MLR), platelet/lymphocyte ratio (PLR), mean platelet volume (MPV), red cell distribution width (RDW), the presence of testicular dysgenesis syndrome (TDS) and its components, postoperative follow-up outcomes were recorded. Patients were divided into two groups as benign and malignant.Results: There was no significant difference between groups in terms of AFP (p=0.116), ?-hCG (p=0.205), LDH (p=0.606), MPV (p=0.087) and RDW (p=0.266); while MLR (p=0.001), NLR (p=0.036) and PLR (p=0.001) were significantly higher in malignant group. The presences of testicular microlithiasis (p=0.719), undescended testis (p=0.254), hypospadias (p=0.645), atrophic testis (p=0.409) were not different between groups; while the rate of disorders of semen parameters (p=0.043) and presence of TDS (p=0.043) were significantly higher in malignant cases. In multivariate analysis, MLR and PLR were found as predictive factors for benign-malign distinction of small testicular masses.Conclusion: In the patients in whom preoperative malignancy suspicion could not be excluded, we think that PLR, MLR, NLR, disorders of semen parameters and presence of TDS may have high predictive value for benign-malign distinction. Partial orchiectomy may be recommended in patients with suspicion of benign lesions according to these parameters.en_US
dc.identifier.doi10.14235/bas.galenos.2019.3266
dc.identifier.endpage55en_US
dc.identifier.issue1en_US
dc.identifier.startpage48en_US
dc.identifier.trdizinid408847en_US
dc.identifier.urihttps://doi.org/10.14235/bas.galenos.2019.3266
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/408847
dc.identifier.urihttps://hdl.handle.net/20.500.14619/10235
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofBezmiâlem Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAdditional preoperative parameters to enable the decision of partial orchiectomy in small testicular massesen_US
dc.typeArticleen_US

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