CAN PLACENTAL HISTOPATHOLOGICAL LESIONS BE A GUIDE TO MATERNAL AND NEONATAL OUTCOMES IN PATIENTS WITH PREECLAMPSIA?

dc.authoridATIGAN, AYHAN/0000-0002-7257-0593
dc.contributor.authorAtigan, Ayhan
dc.contributor.authorKilic, Derya
dc.contributor.authorGuler, Tolga
dc.contributor.authorKarakaya, Yeliz Arman
dc.date.accessioned2024-09-29T16:07:47Z
dc.date.available2024-09-29T16:07:47Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate the predictive role of massive perivillous fibrinoid deposition (MPFD), syncytial knots, and accompanying histopathological features of placentas of preeclampsia (PE) on maternal and neonatal outcomes. Matherials and methods: A retrospective clinicopathological study was conducted in a tertiary unit. In the study, 51 pregnant women admitted with PD and 55 normotensive healthy pregnant women matched for age and gestational age were compared. Information regarding clinical characteristics, neonatal findings, and placental properties such as syncytial knots, vascular structure density, placental area, volume, and weight) was retrieved. Results: Massive perivillous fibrinoid deposition, syncytial knots and decreased vessels in terminal villi were significantly frequent in the PE group compared to the controls. However, these histopathological findings were not associated with clinical and neonatal outcomes. Conclusions: Syncytial knot and perivillous fibrin deposition are significant microscopic findings of preeclampsia. However, the presence and amount of fibrin deposition were not correlated with perinatal outcome.en_US
dc.identifier.doi10.26650/IUITFD.982918
dc.identifier.endpage432en_US
dc.identifier.issn1305-6441
dc.identifier.issue3en_US
dc.identifier.startpage425en_US
dc.identifier.trdizinid1116168en_US
dc.identifier.urihttps://doi.org/10.26650/IUITFD.982918
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1116168
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7166
dc.identifier.volume85en_US
dc.identifier.wosWOS:000800428300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherIstanbul Univ, Fac Medicine, Publ Offen_US
dc.relation.ispartofJournal of Istanbul Faculty of Medicine-Istanbul Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPreeclampsiaen_US
dc.subjectmassive perivillous fibrinoid depositionen_US
dc.subjectsyncytial knotsen_US
dc.subjectneonatal outcomesen_US
dc.subjectobstetric complicationsen_US
dc.titleCAN PLACENTAL HISTOPATHOLOGICAL LESIONS BE A GUIDE TO MATERNAL AND NEONATAL OUTCOMES IN PATIENTS WITH PREECLAMPSIA?en_US
dc.typeArticleen_US

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