Frequency and genotype distribution of high-risk human papilloma virus types in karabuk province, turkey: a hospital based cross-sectional study

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dc.contributor.authorEroğlu, Semra
dc.contributor.authorAsgın, Nergis
dc.date.accessioned2024-09-29T16:32:06Z
dc.date.available2024-09-29T16:32:06Z
dc.date.issued2020
dc.departmentKarabük Üniversitesien_US
dc.description.abstractAim: In this cross-sectional study, we aimed to determine the prevalence and genotype distribution of high-risk human papillomavirus(HPV; HR-HPV) infection in patients admitted to the gynecology and obstetrics outpatient clinics of Karabuk University Training andResearch Hospital.Material and Methods: A total of 402 women aged 18–65 years who were admitted to the gynecology and obstetrics Clinic, KarabukUniversity Training and Research Hospital, between October 2016 and June 2019 were included. The presence of HR-HPV andgenotyping of HPV were investigated using real-time polymerase chain reaction in cervical swab samples.Results: HR-HPV infection was found in 23.9% of women. HR-HPV positivity was detected most commonly in the age group of20–29 years. Regarding genotype distribution among HPV-positive women, the genotypes that included multiple HR-HPV infections(mixed HR-HPV) were the most common genotype (38.5%), followed by HPV-16 (13.1%) and HPV-52 (9.8%).Conclusion: Prevalence of HR-HPV infection was found to be high in our region, with the most commonly observed genotypes beingthose containing mixed HR-HPV. We believe that these results would be helpful during the selection of primary and secondarypreventive measures for cervical cancer while planning vaccination and screening programsen_US
dc.identifier.doi10.5455/annalsmedres.2019.12.787
dc.identifier.endpage769en_US
dc.identifier.issue3en_US
dc.identifier.startpage765en_US
dc.identifier.trdizinid366997en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2019.12.787
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/366997
dc.identifier.urihttps://hdl.handle.net/20.500.14619/11353
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleFrequency and genotype distribution of high-risk human papilloma virus types in karabuk province, turkey: a hospital based cross-sectional studyen_US
dc.typeArticleen_US

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