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Öğe St. Thomas II Kardiyopleji Solüsyonu İle Modifiye Del Nido Kardiyopleji Solüsyonunun Miyokardiyal Etkileri(2020-11-27) Akdeniz, FatmaMyocardial protection is the cornerstone of cardiac surgery and cardioplegic arrest is one of the most widely used myocardial protection methods. Although St Thomas II cardioplegia solution is widely used in adult cardiac surgery, it should be given at short intervals. The aim of this study is to investigate the applicability of Modified del Nido cardioplegia with longer arrest times as an alternative to St Thomas II cardioplegia in adult cardiac surgery. The study was conducted from the retrospective data of patients who underwent elective CABG surgery between December 2017 and December 2018 in the Department of Cardiovascular Surgery of the SBU Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital. According to the type of cardioplegia applied during the surgery, the patients were divided into two separate groups which are ‘modified del Nido cardioplegia solution’ (MDN, n:20) group and the ‘St. Thomas II cardioplegia solution’ (ST II, n:20) group. In this study, postoperative troponin I and CK-MB values, EF measurements, cross-clemp durations and CPB durations, defibrillation requirement, inotropic agent, IABP and pacemaker requirement, hospital and intensive care stay, and in-hospital mortality rates were examined. Although the cross-clemp durations and CPB durations of the groups were shorter in the MDN group, they were not statistically significant (p= 0,968 and p =0,808> ? = 0,05). At postoperative 6th, 12th and 24th hours, the CK-MB values of the ST II group were higher than the MDN group at the statistical significance level (p=0,000, p=0,001, p=0,007 ? = 0,05), while it was significant in the ST II group (p = 0,033