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Investigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Lines
(Kahramanmaras Sutcu Imam Univ Rektorlugu, 2024) Demiriz Yucer, Tugba
In this study, the antiproliferative effects of Pseudopediastrum boryanum isolated and cultured from Tokat Ye & scedil;il & imath;rmak River benthic habitats were investigated with in-vitro experiments. The Anticancer activity of algae extracts was tested in cancer cell lines using the BrdU cell proliferation ELISA method. Vero (African Green Monkey Kidney Tumour Cells) and HeLa (Human Uterine Carcinoma Cells) were examined in concentrations of 100, 250 and 500 mu g mL-1.-1 . As a result of antiproliferative tests, P. boryanum was found to have effective anticancer properties. P. boryanum extract concentrations of 250 and 500 mu g mL-1-1 had a significant cytotoxic effect on Vero and HeLa cell lines after 24 hours. According to the results, P. boryanum is estimated to be a good option for quantitative pharmaceutical analyses and could be evaluated in the pharmaceutical industry.