Investigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Lines

Küçük Resim Yok

Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Kahramanmaras Sutcu Imam Univ Rektorlugu

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

In this study, the antiproliferative effects of Pseudopediastrum boryanum isolated and cultured from Tokat Ye & scedil;il & imath;rmak River benthic habitats were investigated with in-vitro experiments. The Anticancer activity of algae extracts was tested in cancer cell lines using the BrdU cell proliferation ELISA method. Vero (African Green Monkey Kidney Tumour Cells) and HeLa (Human Uterine Carcinoma Cells) were examined in concentrations of 100, 250 and 500 mu g mL-1.-1 . As a result of antiproliferative tests, P. boryanum was found to have effective anticancer properties. P. boryanum extract concentrations of 250 and 500 mu g mL-1-1 had a significant cytotoxic effect on Vero and HeLa cell lines after 24 hours. According to the results, P. boryanum is estimated to be a good option for quantitative pharmaceutical analyses and could be evaluated in the pharmaceutical industry.

Açıklama

Anahtar Kelimeler

Antiproliferative effect, BrdU, Chlorophyta, Pseudopediastrum boryanum

Kaynak

Ksu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Nature

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

27

Sayı

5

Künye