Investigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Lines
Küçük Resim Yok
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kahramanmaras Sutcu Imam Univ Rektorlugu
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, the antiproliferative effects of Pseudopediastrum boryanum isolated and cultured from Tokat Ye & scedil;il & imath;rmak River benthic habitats were investigated with in-vitro experiments. The Anticancer activity of algae extracts was tested in cancer cell lines using the BrdU cell proliferation ELISA method. Vero (African Green Monkey Kidney Tumour Cells) and HeLa (Human Uterine Carcinoma Cells) were examined in concentrations of 100, 250 and 500 mu g mL-1.-1 . As a result of antiproliferative tests, P. boryanum was found to have effective anticancer properties. P. boryanum extract concentrations of 250 and 500 mu g mL-1-1 had a significant cytotoxic effect on Vero and HeLa cell lines after 24 hours. According to the results, P. boryanum is estimated to be a good option for quantitative pharmaceutical analyses and could be evaluated in the pharmaceutical industry.
Açıklama
Anahtar Kelimeler
Antiproliferative effect, BrdU, Chlorophyta, Pseudopediastrum boryanum
Kaynak
Ksu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Nature
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
27
Sayı
5
