Are platelet and eosinophil parameters indicators of predicting the development of erectile dysfunction after radical prostatectomy?

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dc.contributor.authorSelvı, İsmail
dc.contributor.authorÖztürk, Erdem
dc.date.accessioned2024-09-29T16:33:25Z
dc.date.available2024-09-29T16:33:25Z
dc.date.issued2019
dc.departmentKarabük Üniversitesien_US
dc.description.abstractINTRODUCTION: Erectile dysfunction(ED) may develop in 14-90% following radical prostatectomy(RP).Development of ED is due to neurovascular damage during surgery. In our study, we aimed to evaluate whetherthe platelet and eosinophil parameters are prognostic factors in predicting ED after prostatectomy.METHODS: Data of 181 patients who underwent RP between January 2010 and December 2016 were analyzedretrospectively. In the preoperative period, platelet count, mean platelet volume (MPV), platelet distributionwidth (PDW) and eosinophil count were recorded. The patients were evaluated for ED according to theInternational Erectile Function Index in preoperatively and postoperatively. In the postoperative 12th month, EDwas observed in 128 patients following RP. Among them, 82 patients with postoperative ED were included inGroup I, and 46 patients without postoperative ED were included in Group II.RESULTS: Age (p=0.281) and body mass index (p=0.851) had no significant difference between groups. Inpreoperative period, mean platelet count (292.18±51.62 vs. 240.15±46.25, p<0.001), mean MPV value(8.77±1.24 vs. 6.17±0.87, p<0.001) and mean eosinophil count (0.57±0.16 vs. 0.47±0.10, p<0.001) were higher in Group I. Mean PDW value (16.21±1.84 vs.16.75±1.77, p=0.110) had no significantly difference. According toROC analysis, the cut-off values for platelet, MPV and eosinophil were 242 (AUC: 0.783, p<0.001), 7.24 (AUC:0.951, p<0.001) and 0.5 (AUC: 0.675, p=0.001), respectively. In multivariate analysis, MPV and eosinophilwere found to be more important independent factors in predicting ED after RP.DISCUSSION and CONCLUSION: It is shown that platelet, MPV and eosinophil are independent predictivefactors in predicting ED following prostatectomy.en_US
dc.identifier.endpage143en_US
dc.identifier.issn0304-596X
dc.identifier.issue1en_US
dc.identifier.startpage136en_US
dc.identifier.trdizinid314680en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/314680
dc.identifier.urihttps://hdl.handle.net/20.500.14619/11862
dc.identifier.volume52en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofACTA ONCOLOGICA TURCICAen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTıbbi İnformatiken_US
dc.subjectGenel ve Dahili Tıpen_US
dc.subjectTemel Sağlık Hizmetlerien_US
dc.subjectOnkolojien_US
dc.subjectSağlık Bilimleri ve Hizmetlerien_US
dc.titleAre platelet and eosinophil parameters indicators of predicting the development of erectile dysfunction after radical prostatectomy?en_US
dc.typeArticleen_US

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