The localization of CD3, CD79a, CD68 and S100 protein immunoreactive cells in hemal nodes of Saanen goat (Capra hircus)

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dc.contributor.authorBozkurt, Y. A.
dc.contributor.authorKabak, M.
dc.contributor.authorBasak, F.
dc.contributor.authorOnuk, B.
dc.date.accessioned2024-09-29T16:02:50Z
dc.date.available2024-09-29T16:02:50Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractWe investigated the structure of hemal nodes in Saanen goats using immunohistochemical staining. We examined the distribution of CD3 positive T lymphocytes, CD79a positive B lymphocytes, CD68 positive macrophages and S100 protein positive follicular dendritic cells. Hemal nodes of six healty adult female goats were used. Hemal nodes were removed from the thoracic and abdominal cavities. The oval to round hemal nodes were observed especially between the abdominal aorta and vena cava, and near the kidneys and adrenal glands. Tissue sections were stained with Crossmon's modified triple stain to demonstrate general histological structure. The avidin-biotin-peroxidase technique using anti-CD3, anti-CD79a, anti-CD68 and anti-S100 primary antibodies was used for immunohistochemistry. Many CD3 positive T lymphocytes were found in the germinal center of the lymph follicles and in the lymphatic cords of hemal nodes; CD3 positive cells also were observed in the sinuses. CD79a and CD68 positive cells were found at the germinal center of the lymph follicles. In the lymph follicles near the subcapsular sinuses, CD79a and CD68 positive cells were found especially in e areas bordering the mantle zone. S100 positive cells were found in the lymph follicles, lymphatic cords and sinuses.en_US
dc.identifier.doi10.1080/10520295.2018.1479886
dc.identifier.endpage540en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue7en_US
dc.identifier.pmid30185061en_US
dc.identifier.scopus2-s2.0-85053298134en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage536en_US
dc.identifier.urihttps://doi.org/10.1080/10520295.2018.1479886
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5731
dc.identifier.volume93en_US
dc.identifier.wosWOS:000451798700009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthemal nodeen_US
dc.subjectimmunohistochemistryen_US
dc.subjectlymphocytesen_US
dc.subjectSaanen goaten_US
dc.titleThe localization of CD3, CD79a, CD68 and S100 protein immunoreactive cells in hemal nodes of Saanen goat (Capra hircus)en_US
dc.typeArticleen_US

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