Stereological and histological assessment of the umbilical cord in new-born rat

Küçük Resim Yok

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wolters Kluwer Medknow Publications

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background: Umbilical cord plays a crucial role in the continuation of pregnancy by transferring nutrition and oxygen across the placenta to the fetus. We aimed to investigate the morphometrical and histological features of the umbilical cords in new-born rats. Materials and Methods: The adult male and female rats were chosen for matting purpose in the present study. Briefly, ten adult Wistar albino rats (female, n = 5; male, n = 5) were randomly assigned into five groups of two animals (female, n = 1; male, n = 1). Immediately after parturition, two umbilical cords of new-born rats (0-day-old) from each group were randomly selected. Finally, ten umbilical cord samples were examined using the histological and stereological methods in the light and electron microscopes. Results: The total numbers of Hofbauer cells and mesenchymal stromal cells was estimated statistically. We also calculated the mean volume of umbilical cords, arteries and veins, as well as arterial and venous lumens. Our histological findings also exhibited the histological features of Hofbauer cells, mesenchymal stromal cell cells, and blood vessels. Conclusion: Our findings showed more detailed information about umbilical cord tissues and their components, and that may contribute to the diagnose of umbilical cord complications in the developing fetus. © 2020 Journal of Microscopy and Ultrastructure

Açıklama

Anahtar Kelimeler

Hofbauer cell, Mesenchymal stromal cell, New-born rat, Stereology, Umbilical cord

Kaynak

Journal of Microscopy and Ultrastructure

WoS Q Değeri

Scopus Q Değeri

Q3

Cilt

9

Sayı

3

Künye