Hemogram parameters in fibromyalgia and effects of wet cupping therapy on hemogram parameters

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dc.authoridTalay Calis, Havva/0000-0002-8897-8921
dc.authoridBenli, Ali Ramazan/0000-0003-0039-1497
dc.contributor.authorAslaner, Humeyra
dc.contributor.authorcalis, Havva Talay
dc.contributor.authorKarabasc, Caglar
dc.contributor.authorBenli, Ali Ramazan
dc.date.accessioned2024-09-29T16:08:28Z
dc.date.available2024-09-29T16:08:28Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: Wet cupping therapy (WCT) is one of the complementary and traditional therapies that are still must be scientifically interpreted. This study aimed to assess hemogram parameters that are subclinical inflammatory markers in patients with fibromyalgia syndrome (FMS) and observe how they were affected with WCT. Methods: The present study consisted of two groups; patient group included participants who were diagnosed with FMS and who received WCT and control group included healthy participants who received WCT within the concept of preventive medicine. Results: Neutrophil-to-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) values were higher in the patient group (P = 0.029 and P = 0.003, respectively). Considering that the participants had FMS, the optimal cutoff value for PLR was > 1.62, sensitivity was 70%, specificity was 56%, positive predictive value was 61.7%, and negative predictive value was 65.3%. Receiver operating characteristic (ROC) curve revealed a significant sensitivity and specificity (ROC area = 0.664), (confidence interval [CI]: 0.530-0.781) (P < 0.023). The optimal cutoff value for PLR was > 146, sensitivity was 60%, specificity was 83%, positive predictive value was 78%, and negative predictive value was 67%. ROC curve revealed a statistically significant sensitivity and specificity (ROC area = 0.726), (CI: 0.59-0.83) (P < 0.001). The optimal cutoff value for platelet was > 284,000, sensitivity was 83%, specificity was 40%, positive predictive value was 58%, and negative predictive value was 70%. ROC curve revealed a significant sensitivity and specificity (ROC area = 0.65), (CI: 0.51-0.76) (P = 0.036). Conclusion: NLR, PLR, and thrombocyte count parameters can be useful in the process of diagnosing FMS. In addition, NLR, PLR, and MPV decreased in patients who received WCT.en_US
dc.identifier.doi10.4103/wjtcm.wjtcm_73_21
dc.identifier.endpage501en_US
dc.identifier.issn2311-8571
dc.identifier.issn2589-2894
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85138704842en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage497en_US
dc.identifier.urihttps://doi.org/10.4103/wjtcm.wjtcm_73_21
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7565
dc.identifier.volume8en_US
dc.identifier.wosWOS:000863307000003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofWorld Journal of Traditional Chinese Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFibromyalgia syndromeen_US
dc.subjectneutrophil-lymphocyte ratioen_US
dc.subjectplatelet-lymphocyte ratioen_US
dc.subjectwet cupping therapyen_US
dc.titleHemogram parameters in fibromyalgia and effects of wet cupping therapy on hemogram parametersen_US
dc.typeArticleen_US

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