Which adolescent factors predict alcohol misuse in young adulthood? A co-twin comparisons study

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dc.authoridKaprio, Jaakko/0000-0002-3716-2455
dc.authoridSalvatore, Jessica/0000-0001-5504-5087
dc.authoridKsinan, Albert/0000-0003-3900-5098
dc.authoridLatvala, Antti/0000-0001-5695-117X
dc.authoridStephenson, Mallory/0000-0002-1498-4333
dc.contributor.authorStephenson, Mallory
dc.contributor.authorBarr, Peter
dc.contributor.authorKsinan, Albert
dc.contributor.authorAliev, Fazil
dc.contributor.authorLatvala, Antti
dc.contributor.authorViken, Richard
dc.contributor.authorRose, Richard
dc.date.accessioned2024-09-29T16:04:34Z
dc.date.available2024-09-29T16:04:34Z
dc.date.issued2020
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground and aims Research on adolescent predictors of later alcohol misuse is typically conducted on samples of singletons, and associations may be confounded by between-family differences. To address potential confounding, we applied a co-twin comparison design to evaluate whether differences between co-twins in a wide array of adolescent risk factors predicted differences in young adult alcohol misuse. Design Longitudinal study in which associations between characteristics of the sample as adolescents were used to predict young adult alcohol misuse in individual-level analyses and co-twin comparisons. Setting Finland. Participants A total of 3402 individuals (1435 complete twin pairs; 36% monozygotic; 57% female) from the FinnTwin12 study. Measurements The young adult alcohol misuse outcome was a composite score of alcohol use and intoxication frequency. Adolescent predictors included factor scores representing academic performance, substance use, externalizing problems, internalizing problems, peer environment, physical health and relationship with parents; and single measures tapping alcohol expectancies, life events and pubertal development. Findings In individual-level analyses, individuals with higher adolescent substance use, externalizing problems, time with friends, peer deviance, sports involvement, sleeping difficulties, parental discipline, positive alcohol expectancies and difficulty of life events reported higher alcohol misuse in young adulthood (Ps < 0.019, R-2 = 0.0003-0.0310%). Conversely, those with higher adolescent internalizing problems, parent-child relationship quality and time with parents reported lower alcohol misuse (Ps < 0021, R-2 = 0.0018-0.0093%). The associations with adolescent substance use and alcohol expectancies remained significant in co-twin comparisons (Ps < 0.049, R-2 = 0.0019-0.0314%). Further, academic performance emerged as a significant predictor, such that individuals with higher grades compared with their co-twin reported higher young adult alcohol misuse (Ps < 0.029, R-2 = 0.0449-0.0533%). Conclusions Adolescent substance use, positive alcohol expectancies and higher academic performance appear to be robust predictors of later alcohol misuse.en_US
dc.description.sponsorshipNational Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health [R01AA012502, R01AA015416, K02AA018755, K01AA024152]; Academy of Finland [265240, 263278, 308248, 312073]en_US
dc.description.sponsorshipThis work was supported by the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health under award numbers R01AA012502, R01AA015416, K02AA018755 and K01AA024152; and the Academy of Finland (grants 100499, 205585, 118555, 141054, 265240, 263278 and 264146). J.K. has been supported by the Academy of Finland (grants 265240, 263278, 308248, 312073). The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders.en_US
dc.identifier.doi10.1111/add.14888
dc.identifier.endpage887en_US
dc.identifier.issn0965-2140
dc.identifier.issn1360-0443
dc.identifier.issue5en_US
dc.identifier.pmid31746044en_US
dc.identifier.scopus2-s2.0-85077853980en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage877en_US
dc.identifier.urihttps://doi.org/10.1111/add.14888
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6207
dc.identifier.volume115en_US
dc.identifier.wosWOS:000506165800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAddictionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlcoholen_US
dc.subjectadolescenceen_US
dc.subjectco-twin comparisonsen_US
dc.subjectFinnTwin12en_US
dc.subjectfixed effectsen_US
dc.subjectyoung adulthooden_US
dc.titleWhich adolescent factors predict alcohol misuse in young adulthood? A co-twin comparisons studyen_US
dc.typeArticleen_US

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