Effects of drug use on the development of Diabetic Ketoacidosis

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dc.contributor.authorKoyuncu, M.
dc.contributor.authorOzturk, D.
dc.contributor.authorAltinbilek, E.
dc.contributor.authorYapar, N.
dc.contributor.authorKarakisa, H.
dc.contributor.authorKavalci, C.
dc.contributor.authorIkizceli, I.
dc.date.accessioned2024-09-29T16:21:25Z
dc.date.available2024-09-29T16:21:25Z
dc.date.issued2015
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIntroduction: Diabetic Ketoacidosis (DKA) is a condition in which the body must use adipose and protein deposits as intracellular energy sources due to a lack of insulin. In the current study, we aimed to investigate the effects of drug use on the development of DKA and on clinical parameters in patients who presented to the Emergency Department (ED) with the diagnosis of DKA. Materials and methods: This study was retrospectively conducted in Sisli Etfal Training and Research Hospital between October 1, 2011 and March 31, 2013. The following parameters were recorder for each patient: age, gender, complaints, history of drug use, cause of DKA, pH, HCO3 levels, time spent in the ED, treatment outcomes and hospitalization durations. Results: The mean age of the patients was 42.6±18.6 years, and 58% (n=43) of them were female. 20.3% (n=15) of the patients were drug free. 63.5% (n=47) of the patients were followed up with in the ward, 12 (16.5%) were followed up with in the ED and 20% (n=15) were followed up with in the intensive care unit (ICU). The mean duration of stay in the ED was 15 hours, and the mean hospitalization time was 10 days. The mortality rate was 2.7% (n=2). When the effects of the drug use on DKA were examined, there were no statistically significant differences between the patients in terms of acidosis condition, mortality, clinic of hospitalization and durations of follow-up and treatment (p > 0.05). The most important factor causing ketoacidosis was the presence of infection (40.5%, n=30), while the most common symptom was nausea/vomiting (51.4%, n=38). Conclusion: We observed that in patients with DKA, drug use does not affect mortality and morbidity.en_US
dc.identifier.endpage1017en_US
dc.identifier.issn0393-6384
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84945189474en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1013en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14619/9757
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherA. CARBONE Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetic ketoacidosisen_US
dc.subjectEmergency departmenten_US
dc.subjectHyperglycemiaen_US
dc.subjectInfectionsen_US
dc.titleEffects of drug use on the development of Diabetic Ketoacidosisen_US
dc.typeArticleen_US

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