Molecular Panels Used in the Microbiological Diagnosis of Infectious Diarrhea
Küçük Resim Yok
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bilimsel Tip Yayinevi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Acute gastroenteritis, which affects over three billion people worldwide annually, stems from a mix of infectious and non-infectious factors. Infectious gastroenteritis can be attributed to various viral, bacterial, and parasitic agents. The timely detection and treatment of enteropathogens are crucial given their significant impact both on individuals and on society as a whole. Advancements in molecular technology over the past two decades have facilitated the integration of molecular methods into the diagnosis of enteropathogens. Today, various commercial gastrointestinal panels based on molecular methods are being utilized for this purpose. In this review, 938 out of 7854 records retrieved from PubMed, Scopus, and TR Index were included in our study, following the Preferred Reporting Items for Systematic Reviews and Meta -Analyses (PRISMA) guidelines. The purpose, procedure, features, sensitivity, and specificity data, as well as the advantages and disadvantages of existing gastrointestinal panels, have been compiled. Fifteen different panels were identified by grouping syndromic and non-syndromic gastrointestinal panels. With gastrointestinal panels, there are drawbacks such as the inability to identify pathogens in stool that are not covered by the panel, the inability to distinguish between contamination, colonization and infection, and the need for advanced testing to detect antimicrobial resistance. However, it is conceivable that panels could be used as routine diagnostic tests, especially in critically ill patient groups such as immunocompromised patients and children, as they are able to simultaneously detect intestinal pathogens and co -infections, improve workflow, have high sensitivity and specificity and allow for faster turnaround time.
Açıklama
Anahtar Kelimeler
Gastroenteritis, Diarrhea, Diagnonis
Kaynak
Flora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisi
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
29
Sayı
2
