Molecular Panels Used in the Microbiological Diagnosis of Infectious Diarrhea

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dc.contributor.authorColak, Meryem
dc.contributor.authorTas, Esra
dc.date.accessioned2024-09-29T16:09:55Z
dc.date.available2024-09-29T16:09:55Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractAcute gastroenteritis, which affects over three billion people worldwide annually, stems from a mix of infectious and non-infectious factors. Infectious gastroenteritis can be attributed to various viral, bacterial, and parasitic agents. The timely detection and treatment of enteropathogens are crucial given their significant impact both on individuals and on society as a whole. Advancements in molecular technology over the past two decades have facilitated the integration of molecular methods into the diagnosis of enteropathogens. Today, various commercial gastrointestinal panels based on molecular methods are being utilized for this purpose. In this review, 938 out of 7854 records retrieved from PubMed, Scopus, and TR Index were included in our study, following the Preferred Reporting Items for Systematic Reviews and Meta -Analyses (PRISMA) guidelines. The purpose, procedure, features, sensitivity, and specificity data, as well as the advantages and disadvantages of existing gastrointestinal panels, have been compiled. Fifteen different panels were identified by grouping syndromic and non-syndromic gastrointestinal panels. With gastrointestinal panels, there are drawbacks such as the inability to identify pathogens in stool that are not covered by the panel, the inability to distinguish between contamination, colonization and infection, and the need for advanced testing to detect antimicrobial resistance. However, it is conceivable that panels could be used as routine diagnostic tests, especially in critically ill patient groups such as immunocompromised patients and children, as they are able to simultaneously detect intestinal pathogens and co -infections, improve workflow, have high sensitivity and specificity and allow for faster turnaround time.en_US
dc.identifier.doi10.5578/flora.202402886
dc.identifier.endpage193en_US
dc.identifier.issn1300-932X
dc.identifier.issn2602-2842
dc.identifier.issue2en_US
dc.identifier.startpage172en_US
dc.identifier.trdizinid1242291en_US
dc.identifier.urihttps://doi.org/10.5578/flora.202402886
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1242291
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7846
dc.identifier.volume29en_US
dc.identifier.wosWOS:001258536800002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherBilimsel Tip Yayinevien_US
dc.relation.ispartofFlora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisien_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGastroenteritisen_US
dc.subjectDiarrheaen_US
dc.subjectDiagnonisen_US
dc.titleMolecular Panels Used in the Microbiological Diagnosis of Infectious Diarrheaen_US
dc.title.alternativeİnfeksiyöz İshallerin Mikrobiyolojik Tanısında Kullanılan Moleküler Panelleren_US
dc.typeReviewen_US

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