Study on dna binding properties of nickle (ii) phthalocyanine compound with 2-isopropyl-5- methylphenoxy substituents.

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dc.contributor.authorArslantaş, Ali
dc.contributor.authorAgırtaş, M. Salih
dc.date.accessioned2024-09-29T16:33:34Z
dc.date.available2024-09-29T16:33:34Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractI n this study, previously synthesized Ni (II) phthalocyanine compound bearing 2,10,16,24-tetrakis(2-isopropyl-5-methylphenoxy group was chosen for its interaction with calf thymus-DNA. Calf thymus-DNA was used to determine DNA binding properties of Ni (II) phthalocyanine compound. The DNA binding activities of Ni (II) phthalocyanine compound bearing 2-isopropyl-5-methylphenoxy substituent was investigated by using absorption titration, fluorescence emission, cyclic voltammetry, gel elctrophoresis in Tris-HCl buffer at pH 7.0. In addition to above methods, melting point and viscosity experiment were performed to determine the DNA intercation of the compound in Tris-HCl buffer solution. The results showed that Ni (II) phthalocyanine compound binds strongly to calf thymus-DNA via intercalation bindingen_US
dc.identifier.endpage97en_US
dc.identifier.issn2149-2123
dc.identifier.issue2en_US
dc.identifier.startpage91en_US
dc.identifier.trdizinid271564en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/271564
dc.identifier.urihttps://hdl.handle.net/20.500.14619/12002
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofHittite Journal of Science and Engineeringen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleStudy on dna binding properties of nickle (ii) phthalocyanine compound with 2-isopropyl-5- methylphenoxy substituents.en_US
dc.typeArticleen_US

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