Evaluation of the relationship between Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) score and treatment modality and mortality in patients with ileus

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dc.authoridCekmen, Bora/0000-0003-3348-8375
dc.authoridDorter, Melis/0000-0001-6958-6052
dc.contributor.authorBildik, Busra
dc.contributor.authorCekmen, Bora
dc.contributor.authorAtis, Seref Emre
dc.contributor.authorGunaydin, Yahya Kemal
dc.contributor.authorDorter, Melis
dc.date.accessioned2024-09-29T16:06:10Z
dc.date.available2024-09-29T16:06:10Z
dc.date.issued2023
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBACKGROUND: Ileus is a clinical condition defined as obstruction of the intestines and develops as a result of a mechanical obstruction or paralytic etiologies. Small bowel obstructions are primarily referred to as surgical conditions, but conservative treatment is one of the treatment protocols of choice in some of patients. The aim of the present study was to evaluate the effectiveness of hemoglobin, albumin, lymphocyte, and platelet (HALP) score in determining the conservative versus surgical treatment decision, mortality, and length of hospitalization and demonstrate its superiority over other parameters thought to be associated with inflammation in patients with ileus.METHODS: Patients with a diagnosis of ileus were included in the study. Age, gender, comorbidities, selected treatment modality (conservative or surgical), length of hospitalization, and in-hospital mortality were determined and recorded. White blood cell, hemoglobin, platelet, neutrophil, lymphocyte, neutrophil, lymphocyte, urea, creatinine, aspartate aminotransferase (AST), bilirubin, albumin, and C-reactive protein (CRP) levels from biochemistry parameters were recorded. HALP score was calculated and the relationship with mortality, length of hospitalization, and conservative versus surgical treatment decision was analyzed.RESULTS: A total of 286 patients were included in the study. Conservative treatment was used in 245 (85.7%) patients. Mortality was not observed in 262 (91.6%) patients, 24 (8.4%) of the patients were died. HALP score was significantly higher in surviving patients (p=0.045). The median albumin value of the surviving patients was lower than that of the patients who died (p<0.001). The patients with mortality had significantly higher age, urea, creatinine, AST, and CRP values than those without (p=0.002, p<0.001, p<0.001, p<0.001, p<0.001, and p=0.001, respectively). HALP score of patients with conservative treatment was significantly higher (p=0.003) than those who underwent surgical treatment. Lymphocyte value was significantly higher in patients followed up with conservative treatment (p=0.027). Age, urea, creatinine, and CRP scores were higher in patients who underwent surgery (p=0.007, p<0.001, 0.003, and p<0.001, respectively). HALP score demonstrated that sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio values for a HALP score of 28 were 50.6%, 78.0%, 2.3, and 0.63 for predicting conservative treatment (AUC 0.645 [95% confidence interval =0.556-0.735]; p=0.003).CONCLUSION: The HALP score is an important scoring system that may be useful in determining mortality and treatment modality in patients with ileus. We believe that HALP score will contribute positively to the management of patients with a diagnosis of ileus, both in reducing mortality and in determining the appropriate treatment modality.en_US
dc.identifier.doi10.14744/tjtes.2023.68620
dc.identifier.endpage1356en_US
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue12en_US
dc.identifier.pmid38073459en_US
dc.identifier.scopus2-s2.0-85179364200en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1351en_US
dc.identifier.trdizinid1263594en_US
dc.identifier.urihttps://doi.org/10.14744/tjtes.2023.68620
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1263594
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6672
dc.identifier.volume29en_US
dc.identifier.wosWOS:001125282700009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlbuminen_US
dc.subjecthemoglobinsen_US
dc.subjectileusen_US
dc.subjectintestinesen_US
dc.subjectlymphocytesen_US
dc.subjectplateletsen_US
dc.titleEvaluation of the relationship between Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) score and treatment modality and mortality in patients with ileusen_US
dc.typeArticleen_US

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